| Cat. No. |
Product Name |
Information |
| PC-24293 |
HypoxyStat
Hypoxia inducer
|
HypoxyStat is a small molecule that increase oxygen-hemoglobin binding affinity cause tissue hypoxia, binds hemoglobin, induces systemic hypoxia in mice breathing normoxic (21% O2) air. |
| PC-24261 |
SARM1 inhibitor NB-7
SARM1 inhibitor
|
SARM1 inhibitor NB-7 is a potent, selective and uncompetitive inhibitor of the nicotinamide adenine dinucleotide (NAD) hydrolase SARM1 with biochemical IC50 of 0.025 uM, and IC50 of 0.008 uM in SARM-induced cell-death rescue assays. |
| PC-24260 |
SARM1 inhibitor 7
SARM1 inhibitor
|
SARM1 inhibitor 7 is a potent, selective sterile alpha and TIR Motif Containing 1 (SARM1) inhibitor with biochemical IC50 of 0.3 uM (hSARM1). |
| PC-24230 |
Glycyrrhizin
HMGB1 inhibitor, EV-A71 inhibitor
|
Glycyrrhizin (NSC167409, Glycyrrhizic acid) is a direct HMGB1(high mobility group box 1) inhibitor, also is a specific inhibitor of EV-A71, blocks EV-A71 replication both in vivo and in vitro. |
| PC-24222 |
I3MT-3
3MST inhibitor
|
I3MT-3 (HMPSNE, 3MST inhibitor 3) is a potent, selective, cell-membrane permeable inhibitor of 3-Mercaptopyruvate sulfurtransferase (3MST) with IC50 of 2.7 uM. |
| PC-24192 |
Tapencarium
Fat-reducing agent
|
Tapencarium (Utenpanium chloride, RZL-012) is a fat-reducing and small molecule thermogenic regulator, destroys adipocytes by directly disrupting cell membrane integrity. |
| PC-24167 |
Pariceract
GCase activator
|
Pariceract (LTI-291, BIA 28-6156) is an allosteric, CNS-penetrable glucosylceramidase beta (glucocerebrosidase, GCase) activator. |
| PC-24123 |
Dencatistat
CTPS1 inhibitor
|
Dencatistat (STP938) is a potent, orally bioavailable, selective inhibitor of cytidine triphosphate synthase 1 (CTPS1) with IC50 of <100 nM, specifically blocks cell proliferation of the hematological cancers. |
| PC-24108 |
LIBX-A401
ACSL4 inhibitor
|
LIBX-A401 is a potent, selective inhibitor of Acyl-coenzyme A synthetase long-chain family member 4 (ACSL4) with IC50 of 0.38 uM, MST KD of 0.72 uM, with high selectivity over ACSL3 (IC50>50 uM), protects cells from ferroptosis. |
| PC-24061 |
(R)-dMGer
KAI2 agonist
|
(+)-dMGer ((R)-dMGer) is a potent agonist of Karrikin Insensitive 2 (KAI2), inhibits KAI2 hydrolytic activity with IC50 of 0.16 uM. |
| PC-24060 |
dMGer
KAI2 agonist
|
dMGer (DesmethylGerminone) is a potent and selective HTL/KAI2 (KAI2, Karrikin Insensitive 2) agonist, inhibits KAI2-dependent dMYLG hydrolysis with IC50 of 46 nM. |
| PC-24044 |
SRI-37330
TXNIP inhibitor
|
SRI-37330 (TIX100) is an orally available small molecule that regulates TXNIP expression, inhibits endogenous TXNIP mRNA expression (IC50=0.64 uM, INS-1 cells qRT-PCR assays). |
