| Cat. No. |
Product Name |
Information |
| PC-72338 |
AGI-25696
MAT2A inhibitor
|
AGI-25696 (AGI 25696) is a potent and selective inhibitor of methionine adenosyltransferase MAT2A, blocks the growth of MTAP-deleted tumors in vivo. |
| PC-72337 |
MAT2A inhibitor 28
MAT2A inhibitor
|
MAT2A inhibitor 28 (AZ-28) is a potent and selective inhibitor of methionine adenosyltransferase MAT2A with IC50 of 22 nM. |
| PC-72301 |
SW2_110A
CBX8 inhibitor
|
SW2_110A (SW2-110A) is a selective, cell-permeable inhibitor of chromobox homolog protein CBX8, binds CBX8 N-terminal chromodomain (ChD) with Kd of 800 nM. |
| PC-72298 |
CBX6 inhibitor 5
CBX6 inhibitor
|
CBX6 inhibitor 5 is a selective inhibitor of methyllysine reader protein CBX6 with Kd of 0.9 uM, 90×, 20×, 18×, 6×, and 7× selective for CBX6 over CBX1/2/4/7/8, respectively. |
| PC-72270 |
SHR170008
CD73 inhibitor
|
SHR170008 is a highly potent, small molecule CD73 inhibitor with IC50 of 0.05 nM against human CD73 soluble enzyme. |
| PC-72269 |
OP-5244
CD73 inhibitor
|
OP-5244 is a highly potent, orally bioavailable CD73 inhibitor with biochemical IC50 of 0.25 nM. |
| PC-72241 |
CBLC000
FACT inhibitor
|
CBLC000 (CBL0100) is a small molecule histone chaperone FACT inhibitor, activates p53 and inhibits NF-κB with EC50 of 0.06 and 0.03 uM in cell-based p53 and NF-κB reporter assays, respecitvely. |
| PC-72235 |
ENPP1 inhibitor QPS1
ENPP1 inhibitor
|
ENPP1 inhibitor QPS1 (QPS1) is a potent, selective non-competitive inhibitor of Ectonucleotide pyrophosphatase/PDE1 (NPP1, ENPP1) with Ki of 59.3 nM. |
| PC-72215 |
BJP-06-005-3
Pin1 inhibitor
|
BJP-06-005-3 is a potent, selective, covalent, cell-permeable peptide Pin1 inhibitor (Ki=48 nM) that covalently target Cys113, a highly conserved cysteine located in the Pin1 active site. |
| PC-72175 |
OXS007417
AML differentiation inducer
|
OXS007417 (OXS 007417) is a small moelcule that induces differentiation of AML cells in vitro (CD11b increasein HL-60 cell EC50=48 nM) and shows antitumor effects in vivo. |
| PC-72156 |
I194496
CSE inhibitor
|
I194496 (I 194496) is a novel potent, selective inhibitor of cystathionine γ-lyase (CSE) inhibitor with IC50 of 0.79 uM. |
| PC-72155 |
L-Propargylglycine
CSE inhibitor
|
L-Propargylglycine (L-PAG) is the most commonly used, covalently irreversible inhibitor inhibitor of cystathionine γ-lyase (CSE). |
