| Cat. No. |
Product Name |
Information |
| PC-20933 |
GSK898
KMO inhibitor
|
GSK898 is a potent, highly selective kynurenine monooxygenase (KMO) inhibitor with pIC50 of 8.8. |
| PC-20909 |
GPR56 agonist 36
GPR56 agonist
|
GPR56 agonist 36 is a potent selective agonist of adhesion GPCR ADGRG1/GPR56 with EC50 of 2.95 uM. |
| PC-20902 |
Luvadaxistat
DAAO inhibitor
|
Luvadaxistat (TAK-831, NBI-1065844) is a highly potent, selective D-amino acid oxidase (DAAO) inhibitor with IC50 of 14 nM against human recombinant DAAO enzyme. |
| PC-20890 |
Lalistat-1
LAL inhibitor
|
Lalistat 1 (Lalistat 1) is a potent and selective lysosomal acid lipase (LAL) inhibitor with IC50 of 68 nM, shows no significant activity against pancreatic lipase or lipoprotein lipase. |
| PC-20889 |
Lalistat-2
LAL inhibitor
|
Lalistat-2 (L-stat, Lalistat 2) is a specific inhibitor of lysosomal acid lipase (LAL) with IC50 of 152 nM, shows no significant activity against pancreatic lipase or lipoprotein lipase. |
| PC-20871 |
NVP-231
Ceramide kinase inhibitor
|
NVP-231 (NVP231) is a potent, specific, and reversible ceramide kinase (CerK) inhibitor with IC50 of 12 nM. |
| PC-20847 |
C902
LIN28 inhibitor
|
C902 is a small-molecule inhibitor targeting LIN28-let-7 interaction, shows dose-dependent inhibition in an EMSA validation assay with IC50 of 5 uM. |
| PC-20842 |
GCN2iA
GCN2 inhibitor
|
GCN2iA is a potent seletive inhibitor of general control nonderepressible 2 (GCN2) with IC50 of 4.0 nM. |
| PC-20837 |
SRP-001
Analgesic agent
|
SRP-001 is a non-opioid and non-hepatotoxic small molecule ApAP analog, induces analgesia via N-arachidonoylphenolamine (AM404) formation, and generates higher amounts of AM404 than ApAP. |
| PC-20825 |
eEF-2K inhibitor 2C
eEF-2K inhibitor
|
eEF-2K inhibitor 2C (Compound 2C) is a small molecule inhibitor of eukaryotic elongation factor 2 kinase (eEF-2K), binds to the ATP-binding site of eEF-2K. |
| PC-20821 |
PKA inhibitor H89
PKA inhibitor
|
PKA inhibitor H89 (H-89 dihydrochloride) is a potent, selective cAMP-dependent protein kinase A (PKA) inhibitor with IC50 of 48 nM, weakly inhibits PKG, PKC, casein kinases. |
| PC-20817 |
KZR-8445
Sec61 inhibitor
|
KZR-8445 (KZR8445) is a cyclic depsipeptide, client-selective Sec61 inhibitor with IC50 of 100 nM, targets the Sec61 translocon and selectively modulate Sec61-mediated protein biogenesis. |
