| Cat. No. |
Product Name |
Information |
| PC-25184 |
JX-078
LAT1 inhibitor
|
JX-078 is a potent, selective inhibitor of L-type amino acid transporters LAT1 (SLC7A5), inhibits [3H]-L-leucine uptake into HT-29 cells with IC50 of 121 nM, >10-fold selective over in LAT2. |
| PC-25173 |
Pyrabactin
ABA receptor agonist
|
Pyrabactin is a specific, synthetic abscisic acid (ABA) agonist that selectively inhibits seed germination, promotes interactions between HAB1 and PYR1, PYL1 or PYL3. |
| PC-25171 |
Cyanabactin
ABA receptor agonist
|
Cyanabactin is a potent and selective plant hormone abscisic acid (ABA) receptor agonist that preferentially activates Pyrabactin Resistance 1 (PYR1) with low nanomolar potency, exhihibits a wide spectrum of ABA-like activities. |
| PC-25170 |
ABA receptor agonist iCB
ABA receptor agonist
|
ABA receptor agonist iCB is a novel synthetic abscisic acid (ABA) receptor agonist with broad-spectrum activation across the three receptor subtypes, has IC50 of 0.16 uM in seedling establishment inhibition assay. |
| PC-25146 |
BI033
BACH1 inhibitor
|
BI033 is a selective small-molecule BTB and CNC homology 1 (BACH1) inhibitor, specifically binds to BACH1 WT with Kd of 9.0 uM, significantly upregulates HO-1 mRNA and protein expression. |
| PC-25137 |
GI-Y1
GSDMD inhibitor
|
GSDMD inhibitor Y1 (GI-Y1) is a selective gasdermin D (GSDMD) inhibitor, binds to GSDMD with SPR KD of 7.69 uM, shows cardioprotective effects. |
| PC-25115 |
M6766
ERO1α inhibitor
|
M6766 is a potent, selective inhibitor of endoplasmic reticulum oxidoreductase 1α (ERO1α) with IC50 of 1.4 uM and KD of 1.1 uM. |
| PC-25105 |
DEL-S1
SLIT2/ROBO1 inhibitor
|
DEL-S1 is a first-in-class small molecule that binds to SLIT2 and disrupts its interaction with ROBO1 with IC50 of 68.8 uM in TR-FRET assays. |
| PC-25037 |
BMN 349
Z α1-antitrypsin polymerisation inhibitor
|
BMN 349 (Crovozalpon, BMN349) is a specific small molecule inhibitor of Z mutant alpha-1 antitrypsin (Z-AAT) polymerization that preferentially binds Z-AAT and blocks polymerization. |
| PC-25013 |
TREM2 agonist C1
TREM2 agonist
|
TREM2 agonist C1 is a structural analog of VG-3927 and small molecule agonist of triggering receptor expressed on myeloid cells 2 (TREM2) with KD of 71.36 uM in MST assays. |
| PC-25011 |
YT-II-100
CPSF3 inhibitor
|
YT-II-100 is a novel small molecule inhibitor of Cleavage and Polyadenylation Specific Factor 3 (CPSF3), increases the global abundance of R-loops. |
| PC-24839 |
NGI-186
Oligosaccharyltransferase inhibitor
|
NGI-186 is a potent, small molecule inhibitor of oligosaccharyltransferase (OST) with IC50 of 0.06 uM. |
