| Cat. No. |
Product Name |
Information |
| PC-45088 |
SP-420
Iron chelating agent
|
Petadeferitrin (SP-420) is a desferrithiocin analogue and iron chelating agent that has iron-clearing efficiency with ICE value of 26.7, SP-420 is more potent than desferrithiocin. |
| PC-45513 |
HQ-415
Metal chelator, TDP-43 modulator
|
HQ-415 is a derivative of 8-hydroxyquinoline that has selectivity for rescuing the distinct toxicities caused by the expression of TDP-43 with EC50 of 15 uM, α-synuclein or polyglutamine proteins. |
| PC-42072 |
BAPTA
Mg2+ chelator
|
BAPTA is a cell-permeant, calcium-specific chelator with high selectivity over Mg2+. |
| PC-45623 |
GW4869
nSMase inhibitor
|
GW-4869 (GW4869, GW 4869) is a cell-permeable, potent, specific, non-competitive inhibitor of neutral sphingomyelinase (nSMase) with IC50 of 1 uM. |
| PC-42082 |
TPEN
LIN28 inhibitor
|
TPEN (TPEDA) is a potent, cell-permeable inhibitor of LIN28 that abolishes LIN28-mediated oligouridylation with IC50 of 2.5 uM, also is a specific cell-permeable heavy metal chelator. |
| PC-42281 |
GGTI298
GGTase I inhibitor
|
GGTI298 (GGTI-298) is a CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor that inhibits the processing of geranylgeranylated Rap1A with little effect on processing of farnesylated Ha-Ras (IC50s are 3 and >10 uM respectively). |
| PC-28178 |
Naringenin
DENV RdRp inhibitor, MARK4 inhibitor
|
Naringenin is a flavanone in Citrus reticulata Blanco within anti-inflammatory and antioxidant activities, monocarboxylate transporter 1 (MCT1) in Caco-2 cells with Ki of 15-20 uM, also inhibits DENV RNA-dependent RNA polymerase (RdRp), is also a potent inhibitor of MARK4 with IC50 of 4.11 uM. |
| PC-28145 |
FM029
FOXP3-T-bet stabliezer
|
FM029 is a direct FOXP3 targeting small molecule that binds to FOXP3 (SPR KD=1.13 uM), stabilizes the FOXP3-T-bet interaction to represses T-bet-driven IFN-γ production. |
| PC-28105 |
SEP-227900
DAAO inhibitor
|
SEP-227900 is an orally active small molecule D-amino-acid oxidase (DAAO) inhibitor. |
| PC-28104 |
AS057278
DAAO inhibitor
|
AS057278 (MPCA, U-19425) is a potent, selective, orally active and blood-brain barrier (BBB) penetrant D-amino acid oxidase (DAAO) inhibitor with IC50 of 0.91 uM, shows potential anti-psychotic properties, also inhibits adipocyte lipolysis. |
| PC-28054 |
MOG (35-55) mouse, rat
MOG peptide
|
MOG (35-55) mouse, rat is a myelin oligodendrocyte glycoprotein (MOG) peptide derived from the extracellular domain of MOG protein and key immunodominant epitope extensively utilized in the study of autoimmune demyelinating diseases of the central nervous system (CNS), induce experimental autoimmune encephalomyelitis (EAE) in susceptible animal models, particularly C57BL/6 mice. |
| PC-28053 |
MOG(35-55) amide Mouse, Rat
MOG peptide
|
MOG(35-55) peptide (mouse/rat sequence) is a myelin oligodendrocyte glycoprotein (MOG) peptide derived from the extracellular domain of MOG protein and key immunodominant epitope extensively utilized in the study of autoimmune demyelinating diseases of the central nervous system (CNS), induce experimental autoimmune encephalomyelitis (EAE) in susceptible animal models, particularly C57BL/6 mice. |
