| Cat. No. |
Product Name |
Information |
| PC-23804 |
FLIPinB
c-FLIPL inhibitor
|
FLIPinB is a first-in class, specific small molecule inhibitor of c-FLIPL in the caspase-8/c-FLIPL heterodimer, promotes CD95L- and TRAIL-mediated loss of cell viability and cell death. |
| PC-22971 |
CIB-1476
pro-caspase-1 inhibitor
|
CIB-1476 is an irreversible covalent inhibitor of pro-caspase-1 with IC50 of 0.65 uM, covalently targets pro-caspase-1 Cys285 and Cys397, inhibits NLRP3 inflammasome activation. |
| PC-22752 |
Ac-YVAD-cmk
Caspase-1 inhibitor
|
Ac-YVAD-cmk is a tetrapeptide, selective caspase-1 (interleukin-1 beta converting enzyme, ICE) inhibitor with neuroprotective and anti-inflammatory effects, inhibits pyroptosis (caspase-1-activated cell death). |
| PC-49742 |
NS3694
Caspase inhibitor
|
NS3694 (NS 3694) is a specific cell-permeable diarylurea compound that inhibits apoptosome formation and caspase activation, blocks cytochrome c-induced caspase activation in HeLa cell cytosolic extracts with IC50 of 50 uM. |
| PC-73051 |
Procaspase-6 inhibitor 13
Procaspase-6 inhibitor
|
Procaspase-6 inhibitor 13 is a small molecule, noncovalent, allosteric inhibitor of procaspase-6 with KD of 0.38 uM. |
| PC-73050 |
Procaspase-6 inhibitor 12
Procaspase-6 inhibitor
|
Procaspase-6 inhibitor 12 is a small molecule, noncovalent, allosteric inhibitor of procaspase-6 with KD of 0.47 uM. |
| PC-73049 |
PG3d
Caspase-6 inhibitor
|
PG3d (Caspase-6 inhibitor PG3d) is a cell-active, allosteric and irreversible, non-competitive Caspase-6 inhibitor. |
| PC-72960 |
NH-23-C2
Caspase-2 inhibitor
|
NH-23-C2 (Caspase-2 inhibitor NH-23-C2) is a potent, selective and cell-permeable endogenous caspase-2 inhibitor, does not block caspase-3 or caspase-8. |
| PC-63279 |
ML132
Caspase-1 inhibitor
|
ML132 (NCGC-00183434, CID-4462093) is a highly potent, selective Caspase 1 inhibitor with IC50 of 0.023 nM, displays >1,000-fold selectivity over a panel of 9 caspases.. |
| PC-43410 |
BOC-D-FMK
Caspase inhibitor
|
BOC-D-FMK is a cell-permeable, irreversible, broad spectrum caspase inhibitor, inhibits apoptosis stimulated by TNF-α with IC50 of 39 uM. |
| PC-43391 |
VX-765
Caspase-1 inhibitor
|
VX-765 (Belnacasan) is an orally absorbed prodrug of VRT-043198, which is a potent and selective inhibitor of interleukin-converting enzyme/caspase-1 with Ki of 0.8 nM. |
| PC-43046 |
Z-DEVD-FMK
Caspase-3 inhibitor
|
Z-DEVD-FMK is a specific caspase-3 inhibitor with IC50 of 18 uM, inhibits apoptosis. |
