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Ac-Ile-Glu-Thr-Asp-CHO

Chemical Structure : Ac-Ile-Glu-Thr-Asp-CHO

CAS No.: 191338-86-0

Ac-Ile-Glu-Thr-Asp-CHO (Ac-​IETD-​CHO)

货号: PC-28004Not For Human Use, Lab Use Only.

Ac-IETD-CHO (Ac-Ile-Glu-Thr-Asp-CHO) is a potent, specific Caspases-8 inhibitor, inhibits Fas-mediated apoptotic cell death, hemorrhage, and liver failur, also inhibits cytotoxic T lymphocytes induced cell death.

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5 mg ¥1980 In stock
10 mg ¥3280 In stock
25 mg ¥5280 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Ac-IETD-CHO (Ac-Ile-Glu-Thr-Asp-CHO) is a potent, specific Caspases-8 inhibitor, inhibits Fas-mediated apoptotic cell death, hemorrhage, and liver failur, also inhibits cytotoxic T lymphocytes induced cell death.

物理化学性质&存储条件

分子量 502.52
分子式 C21H34N4O10
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(4S,7S,10S,13S)-4-((S)-sec-butyl)-7-(2-carboxyethyl)-13-formyl-10-((R)-1-hydroxyethyl)-2,5,8,11-tetraoxo-3,6,9,12-tetraazapentadecan-15-oic acid

参考文献

1. Han Z, et al. J Biol Chem. 1997 May 16;272(20):13432-6.

2. Garcia-Calvo M, et al. J Biol Chem. 1998 Dec 4;273(49):32608-13.

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