| Cat. No. |
Product Name |
Information |
| PC-23921 |
BDM_76464
IRAP inhibitor
|
BDM_76464 is a potent, selective inhibitor of insulin-regulated aminopeptidase IRAP with IC50 of 23 nM, has >25-fold selecive over ERAP1 and ARAP2. |
| PC-23920 |
BDM_92499
IRAP inhibitor
|
BDM_92499 is a potent, selective inhibitor of insulin-regulated aminopeptidase IRAP with IC50 of 3.4 nM has >150-fold selectivity over ERAP1 and ARAP2. |
| PC-22853 |
Carnosic acid
ERAP1 inhibitor, BCL9/β-catenin inhibitor
|
Carnosic acid (Carnosate) is a highly selective inhibitor targeting the orthosteric site of ERAP1 with IC50 of 10.73 uM, inhibits oxidative stress and inflammation, suppressescell proliferation, and has antibacterial activity, also inhibits the BCL9/β-catenin interaction with Ki of 3.3 uM. |
| PC-22166 |
QHL1
IRAP inhibitor
|
QHL1 is a potent, selective insulin-regulated aminopeptidase (IRAP) inhibitor with IC50 of 320 nM. |
| PC-21877 |
AKST1220
LTA4H inhibitor
|
AKST1220 is a potent, specific leukotriene A4 hydrolase (LTA4H) inhibitor, improves hippocampal dependent memory. |
| PC-21697 |
HFI-419
IRAP inhibitor
|
HFI-419 is a specifc inhibits of insulin-regulated aminopeptidase (IRAP) with Ki of 0.48 uM, potent inhibits the hydrolysis of the dipeptidic substrate L-Leucine-7-amido-4-methylcoumarin with IC50 of 0.4 uM, >1000-fold lower or no affinity for related and unrelated enzymes. |
| PC-21190 |
Bestatin
CD13 inhibitor, LTA4H inhibitor
|
Bestatin (Ubenimex) is a natural, broad-spectrum, and competitive CD13 (Aminopeptidase N)/APN and leukotriene A4 hydrolase inhibitor with anticancer effects. |
| PC-20620 |
Actinonin
Aminopeptidase M inhibitor
|
Actinonin is an isolated antibiotic and shown to be an inhibitor of aminopeptidase M, inhibits enkephalin-degrading enzymes from guinea-pig striatum (enkephalin-aminopeptidase), striatal membrane neutral endopeptidase and soluble dipeptidylaminopeptidase in rat whole brain homogenate with IC50 of 0.39, 5.6 and 1.1 uM, respectively. |
| PC-49177 |
BDM88951
ERAP2 inhibitor
|
BDM88951 (BDM 88951) is a highly potent, selective inhibitor of endoplasmic reticulum aminopeptidase 2 (ERAP2) with IC50 of 19 nM. |
| PC-73107 |
M8891
MetAP-2 inhibitor
|
M8891 (M 8891) is an orally bioavailable, potent, and reversible methionine aminopeptidase 2 (MetAP2) inhibitor with IC50 of 54 nM, Ki of 4.33 nM. |
| PC-72652 |
JNJ-40929837
LTA4H inhibitor
|
JNJ-40929837 (JNJ40929837) is a potent, highly selective, oral leukotriene A4 hydrolase (LTA4H) inhibitor with IC50 of 1.9 nM, demonstrates high potency (IC50=48 nM) in human whole blood ionophore-stimulated LTB4 release assay. |
| PC-72651 |
LYS006
LTA4H inhibitor
|
LYS006 (LY-S006) is a potent, highly selective leukotriene A4 hydrolase (LTA4H) inhibitor with biochemical IC50 of 0.12 nM. |
