欢迎访问ProbeChem中文网站,英文网站请访问www.probechem.com

首页-抗体药物偶连体和PROTACs-ADC Cytotoxin

Request The Product List ofADC Cytotoxin ADC Cytotoxin

Cat. No. Product Name Information
PC-35367

SG3199

ADC payload

SG3199 (SG-3199) is a PBD dimer warhead component of antibody-drug conjugate (ADC) payload tesirine, demonstrates potently cytotoxic against a panel of human solid tumour and haematological cancer cell lines with mean GI50 of 151.5 pM.
PC-43367

Daunorubicin

Topo II inhibitor, ADC cytotoxin

Daunorubicin (Daunomycin, Rubidomycin) is potent topoisomerase II (Topo II) inhibitor, interacts with DNA by intercalation and inhibition of macromolecular biosynthesis in cancer cells.
PC-43366

Daunorubicin hydrochloride

Topo II inhibitor

Daunorubicin (RP13057) hydrochloride is potent topoisomerase II (Topo II) inhibitor, interacts with DNA by intercalation and inhibition of macromolecular biosynthesis in cancer cells.
PC-43365

Daun02

Topoisomerase inhibitor

Daun02 is a prodrug that is converted by β-galactosidase to Daunorubicin and topoisomerase inhibitor, specifically attenuates cocaine-induced locomotor activity , also attenuates cocaine-induced β-galactosidase expression.
PC-60141

SGD-1882

ADC Cytotoxin

SGD-1882 (PBD dimer, Pyrrolobenzodiazepine dimer) is a novel potent DNA-intercalating payload dimer (PBD dimer) payload for antibody-drug conjugates (ADCs).
PC-60140

D211

ADC payload

D211 is a potent DNA-intercalating payload dimer (PBD dimer) payload for antibody-drug conjugates (ADCs), displays picomolar potency against AML cancer cell lines.
PC-70085

Esperamicin A1

ADC payload

Esperamicin A1 is an enediyne antitumor antibiotics of bacterial origin, acts by binding to DNA and causes strand scission, an ADC payload used in development of antibody drug conjugates.
PC-45714

Mertansine

ADC payload

Mertansine (DM1) is a tubulin inhibitor and thiol-containing maytansinoid that create an antibody-drug conjugate (ADC), an ADC payload.
PC-45636

Maytansinol

ADC payload

Maytansinol (Ansamitocin P-0) is a microtubule assembly inhibitor, an ADC payload in development of antibody drug conjugates.
PC-45655

Calicheamicin

ADC payload

Calicheamicin (Calicheamicin γ1) is an enediyne antitumor antibiotic that acts by binding to DNA and causes strand scission, an ADC payload used in development of antibody drug conjugates.
PC-21891

ZD06519

ADC payload

ZD06519 is a novel camptothecin payload for antibody drug conjugates (ADCs) with highp ayload potency (~1 nM).
PC-45656

alpha-Amanitin

α-Amanitin, an 8-Aa cyclic peptide, is an selective inhibitor of RNA polymerase II and III.

Request The Product List

  • *分类名称:
  • *姓名:
  • *邮箱:
  • *公司名称:
  • *国籍:
  • 留言信息:

备案号:沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

联系我们 sales@probechem.com