| Cat. No. |
Product Name |
Information |
| PC-21693 |
SBP-7455
ULK1/2 inhibitor
|
SBP-7455 is a potent, selective and orally active ULK1/2 inhibitor with IC50 of 13 nM (ULK1) and 476 nM (ULK2) in ADP-Glo assays, selectively blocks autophagic flux in TNBC cell lines. |
| PC-21692 |
MR-2088
ULK1/2 inhibitor
|
MR-2088 is a potent and selective ULK1/2 inhibitor with IC50 of 2.0 nM and MST Kd value of 1.5-4.4 nM (ULK1), efficiently inhibits autophagy. |
| PC-72327 |
DCC-3116
ULK1/2 inhibitor
|
DCC-3116 (DCC3116) is a first-in-class, selective inhibitor of ULK1/2 kinases (IC50=4.7/35 nM) and autophagy. |
| PC-35708 |
ULK-100
ULK1 inhibitor
|
ULK-100 (ULK100) is a potent and selective ULK1 inhibitor with in vitro IC50 of 1.6 nM, inhibits ULK2 with IC50 of 2.6 nM. |
| PC-35707 |
ULK-101
ULK1 inhibitor
|
ULK-101 (ULK101) is a potent and selective ULK1 inhibitor with in vitro IC50 of 8.3 nM, inhibits ULK2 with IC50 of 30 nM. |
| PC-63368 |
BL-918
ULK1 inhibitor
|
BL-918 is a small molecule activator of ULK1 with EC50 of 24 nM (243% kinase activity at 100 nM), induces autophagy via the ULK complex in SH-SY5Y cells. |
| PC-43328 |
MRT67307
IKKε/TBK-1 inhibitor, ULK1/2 inhibitor
|
MRT67307 is a potent, dual inhibitor of IKKε and TBK-1 with IC50 of 160 and 19 nM at 0.1 mM ATP in vitro, also potently inhibit ULK1 and ULK2 in vitro (IC50=45 and 38 nM) and block autophagy in cells. |
| PC-63085 |
LYN-1604
ULK1 activator
|
LYN-1604 is a potential ULK1 agonist (enzymatic activity=195.7% at 100 nM and IC50=1.66 uM against MDA-MB-231 cells), displays a good effect on ULK1 activation with an EC50 of 18.94 nM. |
| PC-62383 |
ULK1-IN-1
ULK1 inhibitor
|
ULK1-IN-1 highly potent ULK1 inhibitor with IC50 of 8 nM, with no enough selectivity but sufficient potency, a cellular probe of autophagy.. |
| PC-60144 |
SR-20295
ULK1 inhibitor
|
SR-20295 (SR20295) is a novel potent ULK1 inhibitor with IC50 of 45 nM. |
| PC-60143 |
SR-19871
ULK1 inhibitor
|
SR-19871 is a novel potent ULK1 inhibitor with IC50 of 11 nM. |
| PC-42021 |
MRT68921 hydrochloride
ULK1/2 inhibitor
|
MRT-68921 hydrochloride (MRT68921) is a potent, relatively specific inhibitor of both ULK1 and ULK2 with IC50 of 2.9 and 1.1 nM, respectively. |
