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首页-小分子抑制剂&激动剂-Apoptosis-Caspase-Ac-DEVD-CHO
Ac-DEVD-CHO

Chemical Structure : Ac-DEVD-CHO

CAS No.: 169332-60-9

Ac-DEVD-CHO (Acetyl-Asp-Glu-Val-Asp-aldehyde)

货号: PC-26675Not For Human Use, Lab Use Only.

Ac-DEVD-CHO is a specific inhibitor of apoptosis and reversible caspase-3 inhibitor with Ki of 0.23 nM.

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10 mg ¥2780 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Ac-DEVD-CHO is a specific inhibitor of apoptosis and reversible caspase-3 inhibitor with Ki of 0.23 nM.

物理化学性质&存储条件

分子量 502.48
分子式 C20H30N4O11
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(4S,7S,10S,13S)-7-(2-Carboxyethyl)-4-(carboxymethyl)-13-formyl-10-isopropyl-2,5,8,11-tetraoxo-3,6,9,12-tetraazapentadecan-15-oic acid

参考文献

1. Garcia-Calvo M, et al.nhibition of human caspases by peptide-based and macromolecular inhibitors. J Biol Chem. 1998 Dec 4;273(49):32608-13.

2. Jinglin Wang, et al. A polysaccharide from Lentinus edodes inhibits human colon cancer cell proliferation and suppresses tumor growth in athymic nude mice. Oncotarget. 2017 Jan 3; 8(1): 610-623.

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