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首页-小分子抑制剂&激动剂-Others-Other Targets-AS057278
AS057278

Chemical Structure : AS057278

CAS No.: 402-61-9

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AS057278 (AS-057278, MPCA, U-19425)

货号: PC-28104Not For Human Use, Lab Use Only.

AS057278 (MPCA, U-19425) is a potent, selective, orally active and blood-brain barrier (BBB) penetrant D-amino acid oxidase (DAAO) inhibitor with IC50 of 0.91 uM, shows potential anti-psychotic properties, also inhibits adipocyte lipolysis.

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50 mg ￥1180 In stock
100 mg ￥1880 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

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AS057278 (MPCA, U-19425) is a potent, selective, orally active and blood-brain barrier (BBB) penetrant D-amino acid oxidase (DAAO) inhibitor with IC50 of 0.91 uM, shows potential anti-psychotic properties, also inhibits adipocyte lipolysis.

物理化学性质&存储条件

分子量 126.12
分子式 C5H6N2O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

5-methylpyrazole-3-carboxylic acid

参考文献

1. Sugden MC, et al. Biochem J. 1982 Jun 15;204(3):749-56.

2. Adage T, et al. Eur Neuropsychopharmacol. 2008;18(3):200-214.

3. Gong N, et al. J Pharmacol Exp Ther. 2011 Jan;336(1):282-93.

4. Sugden MC, et al. Metabolism. 1999 Jun;48(6):707-15.

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