| Cat. No. |
Product Name |
Information |
| PC-22448 |
CMFT
MIF inhibitor
|
CMFT is a a small molecule inhibitor of the functional interaction between the transcription factor ICBP90 (a.k.a. UHRF1) and the MIF-794 CATT5-8 promoter microsatellite, inhibits MIF mRNA expression in a -794 CATT5-8 length-dependent manner with an IC50 of 470 nM. |
| PC-22442 |
UCM-13369
NPM1 inhibitor
|
UCM-13369 is a small molecule inhibitor of nucleophosmin 1 (NPM1), inhibits NPM1 expression, downregulates the pathway associated with mutant NPM1 C+, inhibits tumorsphere growth of CSCs. |
| PC-22397 |
UNC9750
IPMK inhibitor
|
UNC9750 is a potent selective inhibitor of inositol phosphate multikinase (IPMK) with IC50 of 31.6 nM, inhibits human glioblastoma cell growth and selectively decreases cellular InsP5 abundance. |
| PC-22384 |
ML281
STK33 inhibitor
|
ML281 is a potent, selective inhibitor of serine/threonine kinase STK33 with IC50 of 14 nM, >500-fold selective over PKA and AurB. |
| PC-22383 |
CDD-2807
STK33 inhibitor
|
CDD-2807 is a highly potent, selective inhibitor of serine/threonine kinase 33 (STK33) with biochemically Kd of 0.02 nM, IC50 of 9.2 nM in NanoBRET assays, induces contraceptive effect. |
| PC-22367 |
SHP1705
CRY2 activator
|
SHP1705 is a small molecule cryptochrome 2 (CRY2) activator and stabilizer, represses the expression of DBP, CRY1, and PER1, reduces glucose intolerance in obese, insulin-resistant mice. |
| PC-22338 |
STL427944
FOXM1 inhibitor
|
STL427944 is a small molecule inhibitor of forkhead box protein M1 (FOXM1), selectively suppresses FOXM1 by inducing the relocalization of nuclear FOXM1 protein to the cytoplasm and promoting its subsequent degradation by autophagosomes. |
| PC-22337 |
STL001
FOXM1 inhibitor
|
STL001 is a small molecule inhibitor of forkhead box protein M1 (FOXM1), suppresses FOXM1 protein levels in a variety of solid tumor-derived cancer cell lines. |
| PC-22336 |
ARN16186
NAAA inhibitor
|
ARN16186 is a potent, specific small molecule inhibitor of N-Acylethanolamine-hydrolyzing acid amidase (NAAA) with IC50 of 23 nM. |
| PC-22333 |
ML257
ABHD10 inhibitor
|
ML257 (ABL303) is a selective inhibitor of α,β-hydrolase domain-containing 10 (ABHD10) with IC50 of 21 nM, >59-fold selectivity over 40+ other serine hydrolases. |
| PC-22304 |
JYQ-173
DJ-1/PARK7 inhibitor
|
JYQ-173 (JYQ173) is a potent, highly selective Parkinson disease protein 7 (PARK7/DJ-1) inhibitor with IC50 of 19 nM, binds covalently and selectively to PARK7 Cys106. |
| PC-22299 |
MTOB sodium
CtBP inhibitor
|
MTOB sodium is a potent C-terminal binding protein (CtBP) inhibitor, inhibits the transactivation activity of CtBP1 and CtBP2. |
