| Cat. No. |
Product Name |
Information |
| PC-72727 |
T417
PBX1 inhibitor
|
T417 (PBX1 inhibitor T417, TCRS-417) is a novel small molecule compound capable of docking to the interface between PBX1 and its cognate DNA target sequence, potently interferes with the PBX1-DNA interaction with IC50 of 6.58 uM. |
| PC-72720 |
FGF23 inhibitor 13a
FGF23 inhibitor
|
FGF23 inhibitor 13a (FGF23-IN-13a) is a ZINC13407541 analogue with enhanced drug-like properties, inhibits FGF23 with IC50 of 0.14 uM. |
| PC-72719 |
ZINC13407541
FGF23 inhibitor
|
ZINC13407541 is a small molecule antagonist for FGF23, inhibits FGF-23 signaling with IC50 of 0.45 uM. |
| PC-72714 |
AAA-10
BSH inhibitor
|
AAA-10 (AAA10) is a second-generation gut-restricted pan-bile salt hydrolase (BSH) enzyme inhibitor. |
| PC-72703 |
NR162
CASK inhibitor
|
NR162 is a specific small molecule inhibitor of CASK (Ca2+/calmodulin-dependent Ser/Thr kinase) with IC50 of 0.08 uM, and ITC binding Kd of 22 nM. |
| PC-72687 |
Ethanimidothioic acid
Scramblase inhibitor
|
Ethanimidothioic acid (R5421) is an inhibitor of platelet scramblase activity. |
| PC-72667 |
UNC10245131
CIB1 inhibitor
|
UNC10245131 (UNC 10245131) is a potent, selective cyclic peptide inhibitor of calcium and integrin binding protein 1 (CIB1) with ITC Kd of 6.17 nM. |
| PC-72664 |
DS96432529
Bone anabolic agent
|
DS96432529 (DS 96432529) is a potent and orally active bone anabolic agent with EC200 value of 0.024 ug/mL. |
| PC-72661 |
Vanin-1 inhibitor 2
Vanin-1 inhibitor
|
Vanin-1 inhibitor 2 is a potent, selective, oral Vanin-1 inhibitor with IC50 of 3.4 and 1.5 nM for human and mouse Vanin-1, respectively. |
| PC-72660 |
PFI-653
Vanin-1 inhibitor
|
PFI-653 (Vanin-1-IN-1) is a highly potent vanin-1 inhibitor with IC50 of 6.8 nM (human Vanin-1). |
| PC-72648 |
ASC inhibitor MM01
ASC inhibitor
|
ASC inhibitor MM01 (MM01) is a first-in-class, specific small-molecule inhibitor of ASC protein that interferes with ASC speck formation, inhibited ASC-mediated pro-Casp-1 activation with IC50 of 0.5 uM. |
| PC-72643 |
TRC102
BER inhibitor
|
TRC102 (Methoxyamine HCl, TRC-102) is a small-molecule base-excision repair (BER) inhibitor, potentiates the cytotoxicity of pemetrexed and reverses resistance by binding to chemotherapy-induced abasic sites in DNA. |
