| Cat. No. |
Product Name |
Information |
| PC-22163 |
MO-I-1151
ASPH inhibitor
|
MO-I-1151 is a second-generation small molecule inhibitor of aspartate β-hydroxylase (ASPH), inhibits cholangiocarcinoma (CCA) cell proliferation and migration. |
| PC-22160 |
KML110
NUCB1 ligand
|
KML110 is a selective ligand for the lipid-binding protein nucleobindin-1 (NUCB1) with IC50 of 9.6 uM. |
| PC-22154 |
OU749
GGT inhibitor
|
OU749 is a potent, species-specific inhibitor of human gamma-glutamyl transpeptidase (GGT) with Ki of 17.6 uM. |
| PC-22076 |
Sulfopin
Pin1 inhibitor
|
Sulfopin is a potent, selective and covalent inhibitor of Pin1 with Ki of 17 nM in FP assay, targets Pin1's active site Cys113, blocks Myc-driven tumors. |
| PC-21999 |
N-chloroacetyltryptamine
AANAT inhibitor
|
N-chloroacetyltryptamine is a potent in vitro and in vivo AANAT acetyltransferase inhibitor with IC50 of 5.2 uM. |
| PC-21945 |
EBP inhibitor 11
EBP inhibitor
|
EBP inhibitor 11 is a potent, selective, brain-penetrant, orally bioavailable inhibitor of emopamil binding protein (EBP) with mGCMS zymo EC50 of 8 nM, and OPC differentiation EC50 of 44 nM. |
| PC-21942 |
PU.1 inhibitor A11
PU.1 inhibitor
|
PU.1 inhibitor A11 is a small molecule inhibitor of transcription factor PU.1 with EC50 of 2.5 nM in reporter assays, moderates the inflammatory response in human iPSC-derived microglia-like cells (iMGLs) by downregulating inflammatory PU.1-target gene expression without affecting hematopoiesis. |
| PC-21926 |
AZ9567
MAT2A inhibitor
|
AZ9567 is a potent, selective methionine adenosyltransferase 2A (MAT2A) inhibitor with IC50 of 1 nM, selectively targets MTAP-deficient cancer cells. |
| PC-21923 |
Epoxykynin
sEH inhibitor
|
Epoxykynin is a potent, selective soluble epoxide hydrolase (sEH) with IC50 of 36 nM, inhibits the hydrolase activity of sEH and modulates kynurenine pathway. |
| PC-21895 |
MAT2A inhibitor 29
MAT2A inhibitor
|
MAT2A inhibitor 29 (AZ-29) is a potent and selective inhibitor of methionine adenosyltransferase MAT2A with IC50 of 27.9 nM. |
| PC-21866 |
Them1 inhibitor U1
Them1 inhibitor
|
Them1 inhibitor U1 is a selective, allosteric small molecule inhibitor of thioesterase superfamily member 1 (Them1) with IC50 of 8.64 uM, selectively bind the Them1 START domain with Kd of 5.97 uM. |
| PC-21865 |
PCiB-3
Phosphatidylcholine synthesis inhibitor
|
PCiB-3 is a small molecule inhibitor capable of inhibiting phosphatidylcholine (PC) biogenesis with IC50 of 0.4 uM, inhibits the phosphatidylethanolamine (PE) methyltransferase activity of Cho2. |
