| Cat. No. |
Product Name |
Information |
| PC-25050 |
NNZ-2591
Neuroprotective agent
|
Ercanetide (NNZ-2591, NNZ 2591) is an analogue of endogenous diketopiperazine cyclo-glycyl-proline (cyclic GP), shows neuroprotective effect. |
| PC-25037 |
Crovozalpon
Z α1-antitrypsin inhibitor
|
Crovozalpon is a small molecule inhibitor of Z-α1-antitrypsin polymerization. |
| PC-25025 |
Rivasterat
Endothelial dysfunction blocker
|
Rivasterat (CU06-1004, Sac-1004) is a small molecule vascular leakage blocker and endothelial dysfunction blocker, inhibits endothelial hyperpermeability induced by VEGF, histamine and thrombin via stabilization of cortical actin ring and AJ proteins at the cell-cell junction. |
| PC-25014 |
MG-257
Galectin-3/TREM2 inhibitor
|
MG-257 is a small molecule ligand of galectin-3, impedes interaction between TREM2 and galectin-3 with IC50 of 91 nM in TR-FRET assays, attenuates TREM2 signaling. |
| PC-25013 |
TREM2 agonist C1
TREM2 agonist
|
TREM2 agonist C1 is a structural analog of VG-3927 and small molecule agonist of triggering receptor expressed on myeloid cells 2 (TREM2) with KD of 71.36 uM in MST assays. |
| PC-25011 |
YT-II-100
CPSF3 inhibitor
|
YT-II-100 is a novel small molecule inhibitor of Cleavage and Polyadenylation Specific Factor 3 (CPSF3), increases the global abundance of R-loops. |
| PC-25008 |
Veonetinib
Tyrosine kinase inhibitor
|
Veonetinib (Example 3) is an effective inhibitor of tyrosine kinase, exhibits IC50 values of 0.1 μM and 0.4 μM in A549 cells and LOVO cells, respectively. |
| PC-24973 |
Progerinin
Lamin A-Progerin inhibitor
|
Progerinin (SLC-D011) is a specific, small molecule binding inhibitor of lamin A and progerin, reduces progerin expression and improves aging phenotypes in vitro and in vivo HGPS models. |
| PC-24963 |
Navepdekinra
IL-17A inhibitor
|
Navepdekinra (DC-806, S 011806, LY4100504) is a potent, oral, next-generation interleukin-17A (IL-17A) inhibitor. |
| PC-24962 |
KL1333
NAD+ modulator, NQO1 substrate
|
KL1333 (Napazimone) is an orally available, small molecule NAD+ modulator, reacts with NAD(P)H:quinone oxidoreductase 1 (NQO1) as a substrate, resulting in increases in intracellular NAD+ levels via NADH oxidation. |
| PC-24950 |
Eloralintide sodium
Amylin receptor agonist
|
Eloralintide sodium (LY3841136) is a selective amylin mimetic and long acting amylin receptor (AMYR) agonist, binds to amylin receptors with high selectivity from calcitonin receptors. |
| PC-24949 |
Eloralintide
Amylin receptor agonist
|
Eloralintide (LY3841136) is a selective amylin mimetic and long acting amylin receptor (AMYR) agonist, binds to amylin receptors with high selectivity from calcitonin receptors. |
