| Cat. No. |
Product Name |
Information |
| PC-38164 |
DSRM-3716
SARM1 inhibitor
|
DSRM-3716 (DSRM3716, 5-iodoisoquinoline) is a potent and selective inhibitor of NADase SARM1 with IC50 of 75 nM, displays selectivity against various NAD metabolizing and pathway enzymes (e.g., NAMPT and NMNAT). |
| PC-38163 |
ITYR-DBRMD
DIO3 inhibitor
|
ITYR-DBRMD is a first-in-class inhibitor of enzyme iodothyronine deiodinase type 3 (DIO3) with antitumor effects both in vitro and in vivo. |
| PC-38162 |
PBENZ-DBRMD
DIO3 inhibitor
|
PBENZ-DBRMD is a first-in-class inhibitor of enzyme iodothyronine deiodinase type 3 (DIO3) with antitumor effects both in vitro and in vivo. |
| PC-38159 |
CADD522
RUNX2 inhibitor
|
CADD522 (CADD-522) is a small molecule that inhibits RUNX2-DNA binding (IC50=10 nM) and decreases RUNX2 transcriptional activity. |
| PC-38158 |
SCL-LMO2 inhibitor 3K7
SCL-LMO2 inhibitor
|
SCL-LMO2 inhibitor 3K7 is a small molecule, specific inhibitor of the SCL-LMO2 PPI, binds directly to LMO2 with Kd of 1.2 uM. |
| PC-38147 |
eCIRP/TREM-1 inhibitor M3
eCIRP/TREM-1 inhibitor
|
eCIRP/TREM-1 inhibitor M3 (RGFFRGG) is a small CIRP-derived peptide that inhibits the eCIRP/TREM-1 interaction. |
| PC-38144 |
InhiTinib
IFN-gamma inhibitor
|
InhiTinib is a small molecule that inhibit interferon (IFN)-gamma production (IC50=52.44 nM) and proliferation of primary CD3+ T cells without inducing cell death. |
| PC-38132 |
UAB126
|
UAB126 (UAB 126) is a novel rexinoid-like small molecule that show positive effects on metabolic syndrome without the known side effects of potent rexinoids. |
| PC-38123 |
SOX11 inhibitor Compound E
SOX11 inhibitor
|
SOX11 inhibitor Compound E (SOX11i) is a small molecule inhibitor of SOX11, bind directly to SOX11-DBD and interfere with DNA binding. |
| PC-38122 |
SOX11 inhibitor Compound R
SOX11 inhibitor
|
SOX11 inhibitor Compound R (SOX11i) is a small molecule inhibitor of SOX11, bind directly to SOX11-DBD and interfere with DNA binding. |
| PC-38115 |
SLC6A19 inhibitor 39
SLC6A19 inhibitor
|
SLC6A19 inhibitor 39 is a potent, selective and orally efficacious inhibitor of neutral amino acid transporter B0AT1 (SLC6A19) with IC50 of 35 nM. |
| PC-38114 |
T-690
Glucosylceramide synthase inhibitor
|
T-690 is a potent, selective, oral inhibitor of glucosylceramide synthase (GCS) with IC50 of 15 nM. |
