| Cat. No. |
Product Name |
Information |
| PC-70232 |
NAPQI
MIF inhibitor
|
NAPQI (N-Acetylimidoquinone) is a toxic byproduct, iminoquinone metabolite of acetaminophen that covalently binds to the active site of macrophage migration inhibitory factor (MIF). |
| PC-70231 |
KIN-1148
IRF3 agonist
|
KIN-1148 (KIN1148) is a small-molecule IRF3 agonist that induces dose-dependent IRF3 nuclear translocation and specific activation of IRF3-responsive promoters. |
| PC-70227 |
WOBE437
Endocannabinoid uptake inhibitor
|
WOBE437 (WOBE-437) is a potent, selective endocannabinoid uptake inhibitor with IC50 of 10 nM, with an outstanding 1,000-fold selectivity over FAAH. |
| PC-70226 |
RX-055
|
RX-055 is tailored WOBE437-derived diazirine-containing photoaffinity probe that irreversibly blocks membrane transport of both endocannabinoids. |
| PC-60419 |
STL127705
Ku70/80 inhibitor
|
STL127705 (Ku70/80 inhibitor) is a novel small molecule inhibitor of the DNA repair protein Ku70/80, disrupts of Ku70/80-DNA interaction with IC50 of 3.5 uM in EMSA assay. |
| PC-60393 |
PBD-150
Glutaminyl cyclase inhibitor
|
PBD150 is a potent glutaminyl cyclase (QC) inhibitor with Ki of 60 nM. |
| PC-60357 |
MPO-IN-28
MPO inhibitor
|
MPO-IN-28 is a potent, irreversible Myeloperoxidase (MPO) inhibitor with IC50 of 44 nM. |
| PC-70176 |
MDL72527
Polyamine oxidase inhibitor
|
MDL72527 is a polyamine oxidase (PAO) inhibitor that inhibits spermine oxidase and N1-acetylpolyamine oxidase with IC50 of 6.1 and 0.02 uM, respectively. |
| PC-70160 |
5S rRNA modificator 2
RNA Probe
|
5S rRNA modificator 2 (NAI) is a novel chemical probe that enable selective 2’-hydroxyl acylation for accurate RNA structural analysis in living cells. |
| PC-70126 |
FPH2
iPSC-Heps inducer
|
FPH2 (BRD-9424) is a small molecule that promotes differentiation of iPS-derived hepatocytes, induces functional proliferation of hepatocytes in vitro, and thus expands mature human primary hepatocytes. |
| PC-70112 |
ATR-101
ACAT-1 inhibitor
|
ATR-101 (PD-132301, Nevanimibe) is a selective and potent inhibitor of ACAT1 with IC50 of 52 nM. |
| PC-60227 |
BOLD-100
|
A promising ruthenium anticancer compound that blocks angiogenesis, endothelial cell proliferation and migration stimulated by VEGF or NO donor agent. |
