| Cat. No. |
Product Name |
Information |
| PC-27242 |
Elamipretide acetate
Antioxidant tetrapeptide
|
Elamipretide acetate (SS-31, MTP-131, Bendavia) is a novel cell-permeable antioxidant tetrapeptide (D-Arg-dimethylTyr-Lys-Phe-NH2) that targets inner mitochondrial membrane and prevents oxidative damage of neuronal cells and other cell types. |
| PC-27230 |
MI-1148
Furin inhibitor
|
MI-1148 is a potent, peptidomimetic furin inhibitor with Ki of 5.5 pM, has significant protective effect against anthrax and diphtheria toxin, shows potent anti-infectious activity against H5N1 and H7N1 avian influenza viruses, West Nile and Dengue virus. |
| PC-27211 |
MEISi-3
MEIS2 inhibitor
|
MEISi-3 is a small molecule MEIS2 inhibitor targeting MEIS2 proteins effectively along with MEIS1, exhibits potent growth inhibition with IC50 of 0.1 μM in SK-BR-3 cells. |
| PC-27204 |
Semax
Neuroactive peptide
|
Semax is a BBB-penetrable, synthetic peptide analog of Adrenocorticotropic hormone (ACTH) (4-10), can form stable complexes with Cu2+, has immunomodulatory, nootropic and neuroprotective activities. |
| PC-27197 |
DHPS inhibitor GC7
DHPS inhibitor
|
GC7 (N1-guanyl-1,7-diaminoheptane) is a high affinity, effective deoxyhypusine synthase (DHPS) inhibitor with Ki of 10 nM, inhibits spermidine-dependent hypusine-eIF5A activation. |
| PC-27196 |
FPTP
NEK9 inhibitor
|
FPTP is a pharmacological small-molecule NEK9 inhibitor with SPR KD of 3.64 uM, inhibits viability of Huh-7 and Hep3b cells with IC50 of 18.7 uM and 22.8 uM. |
| PC-27195 |
MIPO
NEK9 inhibitor
|
MIPO is a pharmacological small-molecule NEK9 inhibitor with SPR KD of 7.72 uM, inhibits viability of Huh-7 and Hep3b cells with IC50 of 18.8 uM and 19.7 uM. |
| PC-27194 |
ICCB280
C/EBPalpha agonist
|
ICCB280 is a specific small molecule C/EBPalpha (C/EBPα) agonist, induces myeloid differentiation of leukemia cell lines by increasing expression of C/EBPα and C/EBPε, and decreasing expression of c-Myc. |
| PC-27187 |
LRI-305
LIF antagonist
|
LRI-305 (LRI305) is a selective antagonist of Leukemia Inhibitory Factor (LIF) receptor (LIFR), effectively inhibits LIF/LIFR interaction with with IC50 of 0.86 uM in Alpha Screen assays. |
| PC-27168 |
Maresin 1
Macrophage proresolving mediator
|
Maresin-1 (Maresin 1, MaR1) is a potent anti-inflammatory and proresolving mediator biosynthesized by macrophages (MΦs), enhances phagocytosis. |
| PC-27147 |
Zinc protoporphyrin IX
HO-1 inhibitor
|
ZnPP-9 (Zinc protoporphyrin IX, ZnPP-9, Zinc protoporphyrin-9) is an orally active and competitive heme oxygenase-1 (HO-1) inhibitor, regulates expression of HO-1 at the transcriptional level, demonstrates potent antitumor effects. |
| PC-27141 |
STK33-IN-1
STK33 inhibitor
|
STK33-IN-1 is a highly potent serine/threonine kinase STK33 inhibitor with IC50 of 7 nM, inhibitsa number of other kinases in addition to STK33. |
