| Cat. No. |
Product Name |
Information |
| PC-24547 |
Fascin inhibitor G2
Fascin inhibitor
|
Fascin inhibitor G2 is a small molecule inhibitor of Fascin (FSCN1), inhibits the actin-bundling function of fascin with IC50 of 5-8 uM, blocks tumour invasion and metastatic colonization. |
| PC-24546 |
NP-G2-029
Fascin inhibitor
|
NP-G2-029 is a specific small molecule inhibitor of Fascin (FSCN1) with IC50 of 0.19 uM in F-actin-bundling assay, decreases the migration of mouse and human breast tumor cells. |
| PC-24478 |
CLEC-2 inhibitor MAS9
CLEC-2 inhibitor
|
MAS9 is a specific small molecule inhibitor targeting the C-type lectin-like receptor-2 (CLEC-2)-podoplanin interaction with IC50 of 4.5 uM, inhibits CLEC-2-mediated platelet aggregation. |
| PC-24451 |
Mitochondrial complex I inhibitor C458
Mitochondrial complex I modulator
|
C458 is a nontoxic mitochondrial complex I (mtCI) inhibitor with highly protective against Aβ toxicity, C458 protects MC65 Tet-Off cells (Aβ expressed) with an EC50 of 4.6 nM. |
| PC-24394 |
BCT1028
BLVRB inhibitor
|
BCT1028 is a potent, selective small molecule Biliverdin IXβ reductase (BLVRB) inhibitor with IC50 of 195 nM (50 uM BLVRB substrate DCPIP). |
| PC-24385 |
HEX-1
Pin1 inhibitor
|
HEX-1 is a valuable addition to the armamentarium against CRC, suppresses the proliferation of cancer cells and tumorigenesis via the inactivation and sensitization of PIN1. |
| PC-24382 |
MitoSNO
Mitochondria S-nitrosating agent
|
MitoSNO (mitochondria-targeted S-nitrosothiol) is a mitochondria-selective S-nitrosating agent, selectively S-nitrosates mitochondrial proteins. |
| PC-24354 |
Fisetin
NUF2 inhibitor, YBX-1 inhibitor
|
Fisetin is a small molecule inhibitor of NUF2, effectively inhibits PCa cell proliferation, also is an inhibitor of Y-box binding protein-1 (YB-1, YBX-1) activation, shows antioxidant, anticancer, neuroprotection effects. |
| PC-24318 |
LPHN2 inhibitor D11
LPHN2 inhibitor
|
LPHN2 inhibitor D11 is a reversible and selective inhibitor of mechanosensitive GPCR latrophilin 2 (LPHN2, ADGRL2), inhibits mechanosensitivity of LPHN2 in HEK293 cells with IC50 of 20 nM. |
| PC-24310 |
NFS1 inhibitor Compound 53
NFS1 inhibitor
|
NFS1 inhibitor Compound 53 is the first potent, selective inhibitor of human cysteine desulfurase (NFS1) with IC50 of 40.5 uM and Ki of 6.4 uM. |
| PC-24307 |
BPRPT0245
PTGR2 inhibitor
|
BPRPT0245 is a specific small-molecule inhibitor of prostaglandin reductase 2 (PTGR2) with IC50 of 8.92 nM, restores 15-keto-PGE2-dependent PPARγ trans-activation in HEK293T cells expressing recombinant PTGR2 with EC50 of 49.22 nM. |
| PC-24295 |
HOSU-53
DHODH inhibitor
|
HOSU-53 (JBZ-001) is a potent and selective inhibitor of DHODH with IC50 of 0.95 nM (hDHODH), exhibits potent antileukemic activity. |
