| Cat. No. |
Product Name |
Information |
| PC-21635 |
Equilin
3βHSD1 inhibitor
|
Equilin (7-Dehydroestrone) is a highly potent 3βHSD1 inhibitor with IC50 of 2.8 nM in VCaP cells, also inhibits the activity of purified 3βHSD1 with SPR KD of 2.23 uM. |
| PC-21595 |
7-Fluorotryptamine
GPRC5A agonist
|
7-fluorotryptamine (7FTA) is a potent synthetic agonist of GPRC5A with EC50 of 7.2 uM for inducing GPRC5A-mediated β-arrestin recruitment. |
| PC-21594 |
7-Fluorotryptamine hydrochloride
GPRC5A agonist
|
7-fluorotryptamine (7FTA) is a potent synthetic agonist of GPRC5A with EC50 of 7.2 uM for inducing GPRC5A-mediated β-arrestin recruitment. |
| PC-21588 |
3-mercaptopicolinic acid hydrochloride
PEPCK inhibitor
|
SKF-34288 (3-Mercaptopicolinic acid) hydrochloride is an orally active phosphoenolpyruvate carboxykinase (PEPCK, PCK) inhibitor with Ki of 2-9 uM, an inhibitor of gluconeogenesis. |
| PC-21580 |
CHD1Li 11
CHD1L inhibitor
|
CHD1Li 11 (CHD1L inhibitor 11) is a small molecule inhibitor of chromodomain helicase DNA-binding protein 1 like (CHD1L) with IC50 of 4.57 uM. |
| PC-21548 |
AEP inhibitor 18
APE inhibitor
|
AEP inhibitor 18 is a potent, selective, orally bioavailable, and brain penetrant inhibitor of asparagine endopeptidase (AEP) with IC50 of 7.8 nM. |
| PC-21475 |
AGI-43192
MAT2A inhibitor
|
AGI-43192 is a potent and selective methionine adenosyltransferase 2A (MAT2A) inhibitor with cellular IC50 of 14 nM. |
| PC-21472 |
RTI-118
NPSR antagonist
|
RTI-118 is a potent, selective neuropeptide S receptor (NPSR, GPR154) antagonist. |
| PC-21471 |
RTI-263
NPSR agonist
|
RTI-263 (SerPheLysAsn-NH2) is a potent, selective tetrapeptide neuropeptide S receptor (NPSR, GPR154) biased agonist with EC50 of 3.02 nM for hNPSR calcium mobilization. |
| PC-21466 |
IOI-214
|
IOI-214 is a potent inhibitor of LPS-induced inflammatory cytokine production, prevent HF diet-induced NAFLD/MAFLD in vivo. |
| PC-21460 |
Brefeldin A
Golgi trafficking inhibitor
|
Brefeldin A is a lactone antibiotic and a specific inhibitor of protein trafficking, blocks the transport of secreted and membrane proteins from endoplasmic reticulum to Golgi apparatus. |
| PC-21459 |
NR5A2 inhibitor Cmp3d2
LRH1 (NR5A2) inhibitor
|
NR5A2 inhibitor Cmp3d2 is a specific small molecule inhibitor of NR5A2 (liver receptor homolog-1, LRH-1) with Kd of 1.8 uM in Biacore-based assays, inhibits the transcriptional activity of hLRH-1 with IC50 of 6 uM (G0S2 mRNA level). |
