Chemical Structure : Equilin
CAS No.: 474-86-2
货号: PC-21635Not For Human Use, Lab Use Only.
Equilin (7-Dehydroestrone) is a highly potent 3βHSD1 inhibitor with IC50 of 2.8 nM in VCaP cells, also inhibits the activity of purified 3βHSD1 with SPR KD of 2.23 uM.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 mg | ¥1580 | In stock | |
| 10 mg | ¥2480 | In stock | |
| 25 mg | ¥3980 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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Equilin (7-Dehydroestrone) is a highly potent 3βHSD1 inhibitor with IC50 of 2.8 nM in VCaP cells, also inhibits the activity of purified 3βHSD1 with SPR KD of 2.23 uM.
Equilin has a higher affinity to 3βHSD1 than BCA.
Equilin suppresses UBE3D-related tumor aggressiveness.
| 分子量 | 268.36 | |
| 分子式 | C18H20O2 | |
| 外观性状 | Solid | |
| 储存条件 |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
(9S,13S,14S)-3-Hydroxy-13-methyl-6,9,11,12,13,14,15,16-octahydro-17H-cyclopenta[a]phenanthren-17-one |
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1. Xuebin Zhang, et al. J Clin Invest. 2023 Dec 15;133(24):e171199.
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