| Cat. No. |
Product Name |
Information |
| PC-21458 |
NR5A2 inhibitor Cmp3
LRH1 (NR5A2) inhibitor
|
NR5A2 inhibitor Cpd3 is a specific small molecule inhibitor of NR5A2 (liver receptor homolog-1, LRH-1) with Kd of 1.5 uM in Biacore-based assays, inhibits the transcriptional activity of hLRH-1 with IC50 of 5 uM (G0S2 mRNA level). |
| PC-21438 |
JYFY-001
Copper chelator
|
JYFY-001 is a small molecule copper chelator with moderate selectivity for targeting copper, potently inhibits cancer proliferation. |
| PC-21429 |
Dp44mT
Iron chelator
|
Dp44mT is an iron chelator with selective anticancer activity, exhibits wide spectrum of potent antitumor activity that overcomes resistance to chemotherapeutics. |
| PC-21411 |
AE1 inhibitor 22
Anion exchanger 1 inhibitor
|
AE1 inhibitor 22 is a small molecule inhibitor of the anion exchanger 1 transporter (AE1) with IC50 of 18 uM. |
| PC-21409 |
ECF inhibitor 1
ECF transporter inhibitor
|
ECF inhibitor 1 is a specific small molecule inhibitor of energy-coupling factor (ECF) transporters, potentially acting as protein-protein interaction (PPI) modulator. |
| PC-21381 |
Mitoquinone mesylate
TRAP1 inhibitor
|
Mitoquinone mesylate (MitoQ) is a potent inhibitor of TRAP1 activity in cancer cells with IC50 of 0.2 uM in 22Rv1 cells, reduces SDHB and SIRT3 and increases phosphor-AMPK and CHOP. |
| PC-21378 |
B3GNT2 inhibitor 8j
B3GNT2 inhibitor
|
B3GNT2 inhibitor 8j is a potent, seletive and orally active inhibitor of β-1,3-N-Acetylglucosaminyltransferase 2 (B3GNT2) with IC50 of 9 nM, shows no activity against B3GNT2 (IC50>250 uM). |
| PC-21360 |
Heparanase-1 inhibitor 18
Heparanase-1 inhibitor
|
Heparanase-1 inhibitor 18 is a potent, selective inhibitor of heparanase-1 (HPSE1) with IC50 of 442 nM. |
| PC-21327 |
ENPP1 inhibitor 29f hydrochloride
ENPP1 inhibitor
|
ENPP1 inhibitor 29f hydrochloride is a potent, orally active inhibitor of ecto-nucleotide pyrophosphatase phosphodiesterase 1 (ENPP1), inhibits the cGAMP hydrolysis by ENPP1 in vitro with IC50 of 68 nM. |
| PC-21293 |
KRP-6
MIF inhibitor
|
KRP-6 is a potent and highly selective macrophage migration inhibitory factor (MIF) ketonase inhibitor with IC50 of 4.31 uM, significantly reduces MIF-induced neutrophil migration. |
| PC-21275 |
ARUK2002821
PI5P4Kα inhibitor
|
ARUK2002821 is a potent, selective PI5P4Kα inhibitor with pIC50 of 8.0, >1000-fold selective over PI5P4Kγ. |
| PC-21268 |
NKG2D inhibitor 4e
NKG2D inhibitor
|
NKG2D inhibitor 4e is a small-molecule protein-protein interaction inhibitor for NKG2D with IC50 of 2.2 uM, disrupts the interaction between NKG2D and multiple protein ligands through allosteric modulation of the NKG2D receptor dimer/ligand interface. |
