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首页-小分子抑制剂&激动剂-Others-Other Targets-SC26196
SC26196

Chemical Structure : SC26196

CAS No.: 218136-59-5

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SC26196 (SC-26196)

货号: PC-22255Not For Human Use, Lab Use Only.

SC26196 (SC-26196) is a potent, selective delta6 desaturase (Δ6 desaturase, D6D, FADS2) inhibitor with IC50 of 0.2 uM in rat liver microsomal assay.

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5 mg ￥1280 In stock
10 mg ￥1880 In stock
25 mg ￥2980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

SC26196 (SC-26196) is a potent, selective delta6 desaturase (Δ6 desaturase, D6D, FADS2) inhibitor with IC50 of 0.2 uM in rat liver microsomal assay.
SC26196 inhibits tumorigenesis in in vivo models of intestinal cancer.
SC26196 enhances radiation therapy in glioblastoma in vitro and in vivo.

物理化学性质&存储条件

分子量 423.56
分子式 C27H29N5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2,2-Diphenyl-5-(4-((pyridin-3-ylmethylene)amino)piperazin-1-yl)pentanenitrile

参考文献

1. Obukowicz MG, et al. J Pharmacol Exp Ther. 1998 Oct;287(1):157-66.

2. Hansen-Petrik MB, et al. Cancer Lett. 2002 Jan 25;175(2):157-63.

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