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首页-小分子抑制剂&激动剂-Others-Other Targets-OR51E2 antagonist C80
OR51E2 antagonist C80

Chemical Structure : OR51E2 antagonist C80

CAS No.: 1241327-01-4

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OR51E2 antagonist C80 (Compound 80)

货号: PC-22324Not For Human Use, Lab Use Only.

OR51E2 antagonist C80 (Compound 80) is an allosteric antagonist and inverse agonist of olfactory receptor OR51E2 with IC50 of 5.2 uM, acts as a negative allosteric modulator (NAM) by significantly decreasing the agonist efficacy.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

OR51E2 antagonist C80 (Compound 80) is an allosteric antagonist and inverse agonist of olfactory receptor OR51E2 with IC50 of 5.2 uM, acts as a negative allosteric modulator (NAM) by significantly decreasing the agonist efficacy.

物理化学性质&存储条件

分子量 447.77
分子式 C15H9ClF3N5O4S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

4-chloro-3-nitro-N-(4-(5-(trifluoromethyl)-1H-1,2,3-triazol-1-yl)phenyl)benzenesulfonamide

参考文献

1. Tatjana Abaffy, et al. Mol Pharmacol. 2024 May 6:MOLPHARM-AR-2023-000843.

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