| Cat. No. |
Product Name |
Information |
| PC-24167 |
LTI-291
GCase activator
|
Pariceract (LTI-291) is an allosteric, CNS-penetrable glucosylceramidase beta (glucocerebrosidase, GCase) activator. |
| PC-24144 |
Larubrilstat
Vanin-1 inhibitor
|
Larubrilstat is a potent, selective vascular non-inflammatory molecule-1 (Vanin 1, VNN1) inhibitor. |
| PC-24143 |
Laporolimus
1504576-27-5
|
Laporolimus is a immunosuppressant. |
| PC-24137 |
Inidascamine
903884-71-9
|
Inidascamine is a small molecule anti-schizophrenia compound. |
| PC-24123 |
Dencatistat
CTPS1 inhibitor
|
Dencatistat (STP938) is a potent, orally bioavailable, selective inhibitor of cytidine triphosphate synthase 1 (CTPS1) with IC50 of <100 nM, specifically blocks cell proliferation of the hematological cancers. |
| PC-24108 |
LIBX-A401
ACSL4 inhibitor
|
LIBX-A401 is a potent, selective inhibitor of Acyl-coenzyme A synthetase long-chain family member 4 (ACSL4) with IC50 of 0.38 uM, MST KD of 0.72 uM, with high selectivity over ACSL3 (IC50>50 uM), protects cells from ferroptosis. |
| PC-24106 |
TPP-UNC-CA157
COQ8A inhibitor
|
TPP-UNC-CA157 is a selective small molecule inhibitor of the archetypal UbiB member COQ8A, inhibits CoQ biosynthesis in cells. |
| PC-24104 |
WJYK50
ASM inhibitor
|
WJYK50 (ASM inhibitor 1c) is a potent, selective inhibitor of acid sphingomyelinase (ASM) with IC50 of 0.48 uM, inhibits the generation of ceramide in a dose-dependent manner. |
| PC-24103 |
ASM inhibitor 4i
ASM inhibitor
|
ASM inhibitor 4i (ASM-IN-1) is a potent, selective inhibitor of acid sphingomyelinase (ASM) with IC50 of 1.5 uM. |
| PC-24088 |
MASP-2, MASP-3 dual inhibitor 45
MASP-2/3 inhibitor
|
MASP-2, MASP-3 dual inhibitor 45 is a potent, dual inhibitor of mannan-binding lectin-associated serine protease MASP-2 and MASP-3 with IC50 of 7.5 nM and 33 nM respectively. |
| PC-24087 |
MASP-2 inhibitor 22
MASP-2 inhibitor
|
MASP-2 inhibitor 22 is a potent, specific small-molecule inhibitor of mannan-binding lectin-associated serine proteases -2 (MASP-2) with IC50 of 8.9 nM, >40-fold selective over MASP-3. |
| PC-24086 |
MASP-2 inhibitor 77
MASP-2 inhibitor
|
MASP-2 inhibitor 77 is a potent, specific small-molecule inhibitor of mannan-binding lectin-associated serine proteases -2 (MASP-2) with IC50 of 11.2 nM, >100-fold selective over MASP-3. |
