| Cat. No. |
Product Name |
Information |
| PC-44669 |
Lucidin
|
Lucidin (NSC 30546) is a mutagenic substance extracted from Rubia tinctorum L., induces DNA repair synthesis in primary rat hepatocytes and transformed C3H/M2-mouse fibroblasts in culture. |
| PC-42293 |
EC330
LIF inhibitor
|
EC330 (EC-330, EC 330) is a first-in-class, orally bioavailable LIF (leukemia inhibitory factor) inhibitor. |
| PC-45088 |
SP-420
Iron chelating agent
|
Petadeferitrin (SP-420) is a desferrithiocin analogue and iron chelating agent that has iron-clearing efficiency with ICE value of 26.7, SP-420 is more potent than desferrithiocin. |
| PC-42072 |
BAPTA
Mg2+ chelator
|
BAPTA is a cell-permeant, calcium-specific chelator with high selectivity over Mg2+. |
| PC-45623 |
GW4869
nSMase inhibitor
|
GW-4869 (GW4869, GW 4869) is a cell-permeable, potent, specific, non-competitive inhibitor of neutral sphingomyelinase (nSMase) with IC50 of 1 uM. |
| PC-42082 |
TPEN
LIN28 inhibitor
|
TPEN (TPEDA) is a potent, cell-permeable inhibitor of LIN28 that abolishes LIN28-mediated oligouridylation with IC50 of 2.5 uM, also is a specific cell-permeable heavy metal chelator. |
| PC-42281 |
GGTI298
GGTase I inhibitor
|
GGTI298 (GGTI-298) is a CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor that inhibits the processing of geranylgeranylated Rap1A with little effect on processing of farnesylated Ha-Ras (IC50s are 3 and >10 uM respectively). |
| PC-25748 |
PKSI-527
Plasma kallikrein inhibitor, PLK inhibitor
|
PKSI-527 is a highly selective plasma kallikrein inhibitor, suppresses collagen-induced arthritis (CIA) by modifying the kallikrein-kinin system, also is a selective PLK inhibitor. |
| PC-25741 |
SB-633825
TIE2 inhibitor, STK10 inhibitor
|
SB-633825 is a potent and ATP-competitive inhibitor of TIE2, LOK (STK10) and BRK with IC50s of 3.5 nM, 66 nM, 150 nM, respectively, inhibits cancer cell growth and angiogenesis. |
| PC-25740 |
STK10 inhibitor 23
STK10 inhibitor
|
STK10 inhibitor 23 is a potent, selective inhibitor of STK10 (serine/threonine kinase 10, LOK) with IC50 of 0.85 uM. |
| PC-25732 |
RUVBL1/2 ATPase-IN-1
RUVBL1/RUVBL2 inhibitor
|
RUVBL1/2 ATPase-IN-1 is a small-molecule inhibitor of RUVBL1/2 ATPase with IC50 of 6.0 uM and 7.7 uM against RUVBL1/2 complex and RUVBL1 respectively. |
| PC-25731 |
RUVBL1/RUVBL2 inhibitor Compound B
RUVBL1/RUVBL2 inhibitor
|
RUVBL1/RUVBL2 inhibitor Compound B is a potent, specific and orally bioavailable RUVBL1/2 ATPase (pontin/TIP49 and reptin/TIP48) inhibitor with IC50 of 59 nM. |
