| Cat. No. |
Product Name |
Information |
| PC-35807 |
OGG1 inhibitor O8
OGG1 inhibitor
|
OGG1 inhibitor O8 is a potent, selective inhibitor of 8-oxoguanine DNA glycosylase 1 (OGG1) with IC50 of 0.22 uM, displays no significant activity against other DNA Glycosylases (NEIL1, NTH1, Fpg, IC50>50 uM). |
| PC-35789 |
NSC 146268
CD151 inhibitor
|
NSC 146268 (NSC146268, 6-Aza-2-thiouridine) is a novel small molecule inhibitor of CD151, inhibits proliferation of metastatic triple negative breast cancer cell lines (MDA-MB 231 and MDA-MB 468, IC50 of 6.0 and 6.2 ug/mL). |
| PC-35767 |
APA modulator T5
Alternative polyadenylation modulator
|
APA modulator T5 is a small modulator of alternative polyadenylation (APA), modulates endogenous APA via nonkinase-mediated pathways and promotes distal-to-proximal (DtoP) APA usage in multiple transcripts. |
| PC-35766 |
APA modulator T4
Alternative polyadenylation modulator
|
APA modulator T4 is a small modulator of alternative polyadenylation (APA) with IC50 of 2.1 uM in reporter assays, modulates endogenous APA via nonkinase-mediated pathways and promotes distal-to-proximal (DtoP) APA usage in multiple transcripts. |
| PC-35759 |
Mosedipimod
|
Mosedipimod (EC-18, 1-palmitoyl-2-linoleoyl-3-acetylglycerol) is a synthetic monoacetyldiaglyceride that stimulates T cell production of IL-2, IL-4, IL-12, IFN-γ, and GM-CSF in vitro. |
| PC-35755 |
PTC299
DHODH inhibitor
|
Emvododstat (PTC299) is a novel potent inhibitor of dihydroorotate dehydrogenase (DHODH), inhibits hypoxia-induced VEGFA protein production in HeLa cells with IC50 of 1.64 nM. |
| PC-35742 |
HB-MIX1902 Supplement (10X)
|
HB-MIX1902 Supplement (10X) is an optimized serum-free supplement used to promote and maintain the growth, maturity and viability of iPS-derived hepatic and biliary cells. MIX1902 is provided as a 10X liquid and is intended to be used with Hepatocyte Culture Medium for optimal viability and prolonged survival of hepatocytes and cholangiocytes. For detaild user guide, please refer to the PC-3574201 User Guide File Below. |
| PC-35735 |
NEK6 inibitor 8
NEK6 inhibitor
|
NEK6 inibitor 8 (ZINC05007751) is a novel inhibitor of the NIMA-related kinase NEK6 with IC50 of 3.4 uM, compound 8 is very selective against NEK1 and NEK6, while no signifcant activity was observed against NEK2, NEK7, and NEK9. |
| PC-35723 |
OSMI-4
O-GlcNAc transferase inhibitor
|
OSMI-4 (OGT inhibitor 4b) is a novel potent, selective, cell-active O-linked N-acetylglucosamine transferase (OGT) inhibitor with EC50 of ~3 uM. |
| PC-35722 |
OGT inhibitor 4a
O-GlcNAc transferase inhibitor
|
OGT inhibitor 4a (OSMI-4 active form) is a novel potent, selective O-linked N-acetylglucosamine transferase (OGT) inhibitor with Kd of 8 nM, the active form of OSMI-4. |
| PC-35706 |
G6PD activator AG1
G6PD activator
|
G6PD activator AG1 (AG1) is a specific, small molecule that increases the activity of the wild-type, Canton mutant (R459L, EC50=3 uM) and several other common glucose-6-phosphate dehydrogenase (G6PD) mutants. |
| PC-35697 |
DKFZ-251
KLK6 inhibitor
|
DKFZ-251 (DKFZ251) is a selective inhibitor of Kallikrein-related peptidase 6 (KLK6) with IC50 of 0.13 uM, demonstrates good selectivity for KLK6 compared to other KLKs. |
