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Ceranib-2

Chemical Structure : Ceranib-2

CAS No.: 1402830-75-4

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Ceranib-2 (Ceranib 2)

货号: PC-25386Not For Human Use, Lab Use Only.

Ceranib-2 (Ceranib 2) is a small molecule ceramidase inhibitor with IC50 of 28 uM in cell-based assays, exhibits antiproliferative effect in SKOV3 cells with IC50 of 0.71 uM, induces the accumulation of multiple ceramide species, decreases levels of sphingosine and S1P.

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10 mg ￥880 In stock
25 mg ￥1380 In stock
50 mg ￥2180 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Ceranib-2 (Ceranib 2) is a small molecule ceramidase inhibitor with IC50 of 28 uM in cell-based assays, exhibits antiproliferative effect in SKOV3 cells with IC50 of 0.71 uM, induces the accumulation of multiple ceramide species, decreases levels of sphingosine and S1P.

物理化学性质&存储条件

分子量 381.43
分子式 C25H19NO3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

3-[3-(4-methoxyphenyl)acryloyl]-4-phenyl-1H-quinolin-2-one

参考文献

1. Draper JM, et al. Mol Cancer Ther. 2011 Nov;10(11):2052-61.

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