| Cat. No. |
Product Name |
Information |
| PC-21519 |
MS102
USP2 inhibitor
|
MS102 is a small molecule, orally available USP2 inhibitor with IC50 of 5.46 uM, induces transient degradation of ACE2 protein and inhibits ACE2-dependent coronavirus infection. |
| PC-21498 |
IMP-2373
DUB CNPy Probe
|
IMP-2373 is a highly targeted cyanopyrrolidine (CNPy) probe for pan-DUB to monitor DUB activity in physiologically relevant live cells. |
| PC-21351 |
MTX115325
USP30 inhibitor
|
MTX115325 (MTX325, MTX-325) is a potent, selective, brain-penetrant USP30 inhibitor with IC50 of 12 nM in biochemical fluorescence polarization assays. |
| PC-21098 |
LN5P45
OTUB2 inhibitor
|
LN5P45 is a selective, covalent, irreversible inhibitor of ubiquitin thioesterase OTUB2 with IC50 of 2.3 uM, strongly induces monoubiquitination of OTUB2 on Lys31. |
| PC-20938 |
OTUDin3
OTUD3 inhibitor
|
OTUDin3 (OTUD3 inhibitor) is a specific, small molecule inhibitor of deubiquitylase OTUD3, binds to OTUD3 (KD=0.32 uM) and inhibits the deubiquitinating activity of OTUD3 by interfering with Ub binding to OTUD3. |
| PC-20656 |
b-AP15
USP14 inhibitor
|
b-AP15 is a specific inhibitor of ubiquitin-specific-processing protease 14 (USP14) and ubiquitin carboxyl-terminal hydrolase isozyme L5 (UCHL5), inhibits DUB activity in purified 19S proteasomes with IC50 of 2.1 uM. |
| PC-20480 |
Neutral Red
USP4 inhibitor
|
Neutral Red is a nitrogenous pH-indicator that can stains lysosomes red, also is a selective, uncompetitive USP4 inhibitor with IC50 of 50 uM. |
| PC-20472 |
IU1-206
USP14 inhibitor
|
IU1-206 is a IU1 derivative with more potent activity against USP14, 10-fold more potent than IU1 and is comparable to the IU1-47. |
| PC-20403 |
PR-619
DUBs inhibitor
|
PR-619 (PR619) is a broad-spectrum, reversible deubiquitinating enzymes (DUBs) inhibitor with IC50 of 3.93 uM-8.87 uM. |
| PC-20202 |
HBX41108
USP7 inhibitor
|
HBX41108 is a specific small-molecule inhibitor of USP7/HAUSP ubiquitin protease with IC50 of 424 nM for inhibition of Ub-AMC hydrolysis by USP7. |
| PC-20190 |
USP14 inhibitor 3
USP14 inhibitor
|
USP14-IN-3 is a specific small molecule USP14 inhibitor with IC50 of <0.5 uM. |
| PC-20189 |
USP14 inhibitor 2
USP14 inhibitor
|
USP14-IN-2 is a specific small molecule USP14 inhibitor with IC50 of <0.5 uM. |
