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首页-小分子抑制剂&激动剂-Proteasome/Ubiquitin-Deubiquitinase (DUB)-NK036
NK036

Chemical Structure : NK036

CAS No.: 2616726-60-2

NK036 (NK-036)

货号: PC-24536Not For Human Use, Lab Use Only.

NK036 is a solubility-enhanced derivative of USP30 inhibitor Compound 39 (CMPD-39), has IC50 of 7.4 nM and 4.1 nM for human USP30 (construct 1 (c1) and USP ch3, respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

NK036 is a solubility-enhanced derivative of USP30 inhibitor Compound 39 (CMPD-39), has IC50 of 7.4 nM and 4.1 nM for human USP30 (construct 1 (c1) and USP ch3, respectively.
NK036 is a potent USP30 inhibitor for co-crystallization studies.

物理化学性质&存储条件

分子量 513.58
分子式 C26H28FN3O5S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-4-fluoro-N-(1-((4-(N-(1-hydroxy-2-methylpropan-2-yl)sulfamoyl)phenyl)amino)-1-oxo-3-phenylpropan-2-yl)benzamide

参考文献

1. Kazi NH, et al. Nat Struct Mol Biol. 2025 May 5.

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