| Cat. No. |
Product Name |
Information |
| PC-26071 |
ADT-030
PDE10A inhibitor
|
ADT-030 is a potent, selective Phosphodiesterase 10A (PDE10A) inhibitor, inhibits enzymatic activity of recombinant PDE10 using cAMP and cGMP as substrates with IC50 of 0.95 uM and 1.15 uM respectively. |
| PC-25901 |
Cilostamide
PDE3 inhibitor
|
Cilostamide (OPC3689) is a potent, selective PDE3 inhibitorwith IC50 of 27 nM and 50 nM for PDE3A and PDE3B, respectively, shows antithrombotic and anti-intimal hyperplastic activity. |
| PC-25900 |
Milrinone
PDE3 inhibitor
|
Milrinone (Win 47203) is a potent, selective PDE3 inhibitor with IC50 of 280 nM and 440 nM for PDE3B and PDE3A respectively. |
| PC-25896 |
GSK4394835A
PDE3B inhibitor
|
GSK4394835A is a selective PDE3B inhibitor with pIC50 of 6.2, >20-fold selective over PDE3A. |
| PC-25668 |
BRD9500
PDE3 inhibitor
|
BRD9500 is a potent, selective and orally active phosphodiesterases 3 (PDE3) inhibitor with IC50 of 10 and 27 nM for PDE3A and PDE3B, respectively. |
| PC-25123 |
ENPP1 inhibitor 31
ENPP1 inhibitor
|
ENPP1 inhibitor 31 is a highly potent ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1, PC-1) inhibitor with IC50 of 14.68 nM, effectively activates the STING pathway in cell lines. |
| PC-25102 |
Vizenpistat
ENPP1 inhibitor
|
Vizenpistat (SR-8541A) is a potent, selective ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (ENPP1) inhibitor. |
| PC-24673 |
ISM5939
ENPP1 inhibitor
|
ISM5939 is a potent and selective, orally bioavailable ENPP1 inhibitor with IC50 of 0.63 nM against the 2,3-cGAMP degradation and 9.28 nM against ATP hydrolysis. |
| PC-23896 |
PDE7A inhibitor 26
PDE7A inhibitor
|
PDE7A inhibitor 26 (PDE7A-IN-1) is a potent, selective PDE7A inhibitor with IC50 of 3.7 nM, 54-fold selective over PDE7B. |
| PC-23567 |
ENPP1 inhibitor VIR3
ENPP1 inhibitor
|
VIR3 is a potent, orally bioavailable Enpp1 with IC50 of <0.75 nM for ENPP1 cGAMP hydrolysis activity inhibition in in vitro assays. |
| PC-23482 |
BC11-38
PDE11 inhibitor
|
BC11-38 is a potent and selective PDE11 inhibitor with IC50 of 0.28 uM, without acitivity against PDE1-10. |
| PC-23191 |
PDE11A4 inhibitor 14b
PDE11A4 inhibitor
|
SMQ-03-20 (PDE11A4 inhibitor 14b) is a potent, selective, brain-penetrant PDE11A4 inhibitor with IC50 of 53 nM, cAMP EC50 of 4.3 uM. |
