| Cat. No. |
Product Name |
Information |
| PC-42698 |
Cilomilast
PDE4 inhibitor
|
Cilomilast (SB207499) is a potent and selective PDE4 inhibitor with IC50 of 95/120 nM for LPDE4/HPDE4. |
| PC-45822 |
PF-2545920 hydrochloride
PDE10A inhibitor
|
PF-2545920 hydrochloride (Mardepodect) potent and selective PDE10A inhibitor with IC50 of 0.37 nM. |
| PC-45821 |
PF-2545920
PDE10A inhibitor
|
PF-2545920 (Mardepodect, MP-10) is a potent and selective PDE10A inhibitor with IC50 of 0.37 nM. |
| PC-45440 |
Avanafil
PDE5 inhibitor
|
Avanafil (TA1790) is a potent and highly selective PDE5 inhibitor (IC50=5.2 nM) for erectile dysfunction. |
| PC-42235 |
SCH00013
Cardiotonic agent
|
SCH00013 is a cardiotonic agent that acts as a calcium sensitizer with no chronotropic activity in mammalian cardiac muscle, elicits positive inotropic effect in dog and rabbit ventricular muscles (EC50=9.2 uM). |
| PC-28251 |
OPC-33540
PDE3 inhibitor
|
OPC-33540 (OPC33540) is a potent, highly selective and competitive PDE3 inhibitor with IC50 of 0.32 nM and 1.5 nM for PDE3A and PDE3AB respectively. |
| PC-28060 |
PDE7-IN-3
PDE7 inhibitor
|
PDE7-IN-3 is a highly potent phosphodiesterase 7 (PDE7) with Ki of 1.9 nM (PDE7A), shows potential for treating neuropathic pain. |
| PC-28059 |
PDE7-IN-2
PDE7 inhibitor
|
PDE7-IN-2 is a potent phosphodiesterase 7 (PDE7) with IC50 of 2.1 uM. |
| PC-27465 |
Giclanfentrine
PDE3/4 inhibitor
|
Giclanfentrine (TQC3721) is a potent, selective phosphodiesterase PDE3/PDE4 dual inhibitor. |
| PC-27424 |
Envogmilast
PDE4 inhibitor
|
Envogmilast is a potent, selective PDE4 inhibitor. |
| PC-26399 |
Zinc42657360
PDE10A inhibitor
|
Zinc42657360 is a phosphodiesterase 10A (PDE10A) inhibitor with IC50 of 1.6 uM. |
| PC-26397 |
DNS-0056
PDE1B inhibitor
|
DNS-0056 is a potent, selective, orally bioavailable and brain-penetrating PDE1B inhibitor with IC50 of 26 nM, 40-fold selective over PDE10A. |
