Phosphodiesterase (PDE) (inhibitors, antagonists, agonists)-ProbeChem.com

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Cat. No.	Product Name	Information
PC-45080	Rolipram PDE4 inhibitor	Rolipram (SB95952, ZK62711) is a potent, selective inhibitor of phosphodiesterases PDE4 with IC50 of 3 nM, 130 nM and 240 nM for PDE4A, PDE4B, and PDE4D, respectively.
PC-45736	AN3199 PDE4 inhibitor	AN3199 is a potent PDE4 inhibitor with IC50 of 94.5 nM.
PC-42760	Crisaborole PDE4 inhibitor	Crisaborole (AN-2728) is a potent PDE4 inhibitor with IC50 of 0.49 uM.
PC-45282	Cilostazol PDE3 inhibitor	Cilostazol (OPC 13013, OPC 21) is a potent, selective inhibitor of PDE3A with IC50 of 0.2 uM.
PC-45441	Udenafil PDE5 inhibitor	Udenafil (DA-8159) is a potent and selective phosphodiesterase 5 (PDE5) inhibitor, inhibits PDE5 activity in rabbit and human platelets with IC50 of 5.84 nM and 8.2 nM, respectively.
PC-42698	Cilomilast PDE4 inhibitor	Cilomilast (SB207499) is a potent and selective PDE4 inhibitor with IC50 of 95/120 nM for LPDE4/HPDE4.
PC-45822	PF-2545920 hydrochloride PDE10A inhibitor	PF-2545920 hydrochloride (Mardepodect) potent and selective PDE10A inhibitor with IC50 of 0.37 nM.
PC-45821	PF-2545920 PDE10A inhibitor	PF-2545920 (Mardepodect, MP-10) is a potent and selective PDE10A inhibitor with IC50 of 0.37 nM.
PC-45440	Avanafil PDE5 inhibitor	Avanafil (TA1790) is a potent and highly selective PDE5 inhibitor (IC50=5.2 nM) for erectile dysfunction.
PC-42235	SCH00013 Cardiotonic agent	SCH00013 is a cardiotonic agent that acts as a calcium sensitizer with no chronotropic activity in mammalian cardiac muscle, elicits positive inotropic effect in dog and rabbit ventricular muscles (EC50=9.2 uM).
PC-25902	NSP-513 PDE3 inhibitor	NSP-513 is a potent and selective phosphodiesterase 3 (PDE 3) inhibitor, shows antiplatelet, antithrombotic, and hemodynamic effects.
PC-25901	Cilostamide PDE3 inhibitor	Cilostamide (OPC3689) is a potent, selective PDE3 inhibitorwith IC50 of 27 nM and 50 nM for PDE3A and PDE3B, respectively, shows antithrombotic and anti-intimal hyperplastic activity.

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