| Cat. No. |
Product Name |
Information |
| PC-45736 |
AN3199
PDE4 inhibitor
|
AN3199 is a potent PDE4 inhibitor with IC50 of 94.5 nM. |
| PC-42760 |
Crisaborole
PDE4 inhibitor
|
Crisaborole (AN-2728) is a potent PDE4 inhibitor with IC50 of 0.49 uM. |
| PC-45282 |
Cilostazol
PDE3 inhibitor
|
Cilostazol (OPC 13013, OPC 21) is a potent, selective inhibitor of PDE3A with IC50 of 0.2 uM. |
| PC-45441 |
Udenafil
PDE5 inhibitor
|
Udenafil (DA-8159) is a potent and selective phosphodiesterase 5 (PDE5) inhibitor, inhibits PDE5 activity in rabbit and human platelets with IC50 of 5.84 nM and 8.2 nM, respectively. |
| PC-42698 |
Cilomilast
PDE4 inhibitor
|
Cilomilast (SB207499) is a potent and selective PDE4 inhibitor with IC50 of 95/120 nM for LPDE4/HPDE4. |
| PC-45822 |
PF-2545920 hydrochloride
PDE10A inhibitor
|
PF-2545920 hydrochloride (Mardepodect) potent and selective PDE10A inhibitor with IC50 of 0.37 nM. |
| PC-45821 |
PF-2545920
PDE10A inhibitor
|
PF-2545920 (Mardepodect, MP-10) is a potent and selective PDE10A inhibitor with IC50 of 0.37 nM. |
| PC-45440 |
Avanafil
PDE5 inhibitor
|
Avanafil (TA1790) is a potent and highly selective PDE5 inhibitor (IC50=5.2 nM) for erectile dysfunction. |
| PC-42235 |
SCH00013
Cardiotonic agent
|
SCH00013 is a cardiotonic agent that acts as a calcium sensitizer with no chronotropic activity in mammalian cardiac muscle, elicits positive inotropic effect in dog and rabbit ventricular muscles (EC50=9.2 uM). |
| PC-25743 |
Icariin
PDE5 inhibitor, PPARα activator
|
Icariin is a flavonol glycoside that inhibits PDE5 and PDE4 activities with IC50 of 432 nM and 73.50 μM, respectively, also is a PPARα activator, also is a small-molecule inducer that promotes G3BP1-driven biomolecular condensate formation, interacts with the N-terminal nuclear transport factor 2-like (NTF2L) domain of G3BP1. |
| PC-25668 |
BRD9500
PDE3 modulator
|
BRD9500 is a potent, selective and orally active phosphodiesterases 3 (PDE3) inhibitor with IC50 of 10 and 27 nM for PDE3A and PDE3B, respectively. |
| PC-25667 |
Zardaverine
PDE3/4 inhibitor
|
Zardaverinea is a potent, specific PDE III/IV (PDE3/4) inhibitor, inhibits PDE III from human platelets and the rolipram-inhibitable PDE IV from canine trachea and human polymorphonuclear (PMN) cells with IC50 of 0.58, 0.79 and 0.17uM, respectively. |
