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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Phosphodiesterase (PDE)-(S)-C33
(S)-C33

Chemical Structure : (S)-C33

CAS No.: 2066488-39-7

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(S)-C33 (C33(S))

货号: PC-60608Not For Human Use, Lab Use Only.

(S)-C33 is a potent, selective PDE9A inhibitor with IC50 of 11 nM, >45-fold selectivity over other PDE isoforms.

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5 mg ￥1880 In stock
10 mg ￥2980 In stock
25 mg ￥4980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

(S)-C33 is a potent, selective PDE9A inhibitor with IC50 of 11 nM, >45-fold selectivity over other PDE isoforms.
(S)-C33 shows better selectivity than (R)-C33 against PDE5.

物理化学性质&存储条件

分子量 357.842
分子式 C18H20ClN5O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(S)-6-((1-(4-chlorophenyl)ethyl)amino)-1-cyclopentyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one

参考文献

1. Huang M, et al. Mol Pharmacol. 2015 Nov;88(5):836-45.

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