| Cat. No. |
Product Name |
Information |
| PC-23991 |
IHCH9033
class I HDAC inhibitor
|
IHCH9033 is a selective, triazole-containing class I HDAC inhibitor, exhibits an increased antitumor effect in FLT3-ITD AML through effectively eliminating leukemia burden and overcoming resistance to FLT3i. |
| PC-23970 |
RG2833
HDAC1/3 inhibitor
|
RG2833 (RGFP109) is a potent, orally bioavailable, brain-penetrant histone deacetylase HDAC1/3 inhibitor with IC50 of 60/50 mM respectively. |
| PC-23965 |
HDAC3 inhibitor LSQ-28
HDAC3 inhibitor
|
LSQ-28 is a potent, selective HDAC3 inhibitor with IC50 of 42 nM, >150-fold selective over HDAC1, HDAC2, and HDAC6. |
| PC-23420 |
4-phenylbutyric acid
HDAC inhibitor
|
4-phenylbutyric acid (4-PBA) is a specific endoplasmic reticulum (ER) stress inhibitor, inhibits HDAC activity and increases histone acetylation levels. |
| PC-22801 |
HDAC6 inhibitor 5a
HDAC6 inhibitor
|
HDAC6 inhibitor 5a (MPI_5a, MPI-5a) is a potent and selective HDAC6 inhibitor with IC50 of 36 nM, >50-fold selectivity over other HDACs. |
| PC-22791 |
Givinostat
HDAC inhibitor
|
Givinostat (ITF-2357) is a potent, orally active, pan-HDAC inhibitor with IC50 of 198 and 157 nM for HDAC1 and HDAC3, respectively. |
| PC-22427 |
PCI-34051
HDAC8 inhibitor
|
PCI-34051 is a potent, specific HDAC8 inhibitor with IC50 of 10 nM, >200-fold selectivity over other HDAC isoforms. |
| PC-22104 |
STR-V-53
HDAC inhibitor
|
STR-V-53 is a novel glycosylated, liver cancer-selective histone deacetylase (HDAC) inhibitor with IC50 of 24.3/60.1/213.43 nM for HDAC1/2/3/6, demonstrates exquisite selective cytotoxicity against human HCC cells. |
| PC-21844 |
RBC1HI
HDAC1/2 inhibitor
|
RBC1HI (Regenacy Brain Class I HDAC Inhibitor) is a novel specific small molecule HDAC1/HDAC2 inhibitor, attenuates behavioral manifestations of oxycodone withdrawal, especially in mice with neuropathic pain. |
| PC-21608 |
CM-444
HDAC inhibitor
|
CM-444 is a potent histone deacetylase (HDAC) inhibitor with IC50 of 7/51/18/531 nM for HDAC1/2/3/6 respectively, also inhibits DNMT1 with IC50 of 2160 nM. |
| PC-21537 |
HR488B
HDAC1 inhibitor
|
HR488B is a potent, selective HDAC1 inhibitor with IC50 of 1.24 uM, effectively inhibits the proliferation of CRC cells. |
| PC-21412 |
Quisinostat
HDAC inhibitor
|
Quisinostat (JNJ-26481585) is potent, second-generation histone deacetylase (HDAC) inhibitor with IC50 of 0.11 nM-0.64 nM for HDAC1, HDAC2, HDAC4, HDAC10 and HDAC11. |
