| Cat. No. |
Product Name |
Information |
| PC-42671 |
Valproic acid sodium salt
HDAC inhibitor
|
Valproic acid sodium salt is a HDAC inhibitor that selectively inhibits the catalytic activity of class I HDACs, and induces proteasomal degradation of HDAC2. |
| PC-42670 |
Valproic acid
HDAC inhibitor
|
Valproic acid is a HDAC inhibitor that selectively inhibits the catalytic activity of class I HDACs, and induces proteasomal degradation of HDAC2. |
| PC-42421 |
EDO-S101
HDAC inhibitor, DNA alkylator
|
EDO-S101 (Tinostamustine) is a fusion molecule comprising of the alkylator bendamustine and the HDAC-inhibitor vorinostat. |
| PC-42767 |
Abexinostat
HDAC inhibitor
|
PCI-24781 (Abexinostat, CRA 024781) is a broad spectrum HDAC inhibitor, inhibits pure recombinant HDAC1 with Ki of 7 nM. |
| PC-42126 |
HDACi-4b
HDAC inhibitor
|
A benzamide-type HDAC inhibitor with IC50 of 78 uM for changes of FXN mRNA in affected GM15850 cells. |
| PC-28562 |
HDAC1 inhibitor L17h
HDAC1 inhibitor
|
HDAC inhibitor L17h is a potent and highly selective HDAC1 inhibitor, transcriptionally upregulates acyl-CoA synthetase long-chain family member 4 (ACSL4) expression, potentiates ferroptosis with arachidonic acid in ESCC. |
| PC-28356 |
CBHA
HDAC inhibitor
|
CBHA (m-Carboxycinnamic acid bishydroxamide) is a competitive and cell-permeable HDAC1 and HDAC3 inhibitor, cause accumulation of hyperacetylated histone H4 in cultured cells. |
| PC-28355 |
SBHA
HDAC inhibitor
|
SBHA (Suberoyl bis-hydroxamic acid) is a competitive and cell-permeable HDAC1 and HDAC3 inhibitor with ID50 values of 0.25 μM and 0.30 μM, respectively, renders MM cells susceptible to apoptosis and facilitates the mitochondrial apoptotic pathways. |
| PC-27750 |
BHC-13
HDAC8 inhibitor
|
BHC-13 is a potent, selective HDAC8 inhibitor. |
| PC-27749 |
BHC-10
HDAC8 inhibitor
|
BHC-10 is a potent, selective HDAC8 inhibitor. |
| PC-27747 |
HDAC8 inhibitor Compound 4
HDAC8 inhibitor
|
HDAC8 inhibitor Compound 4 is a potent and selective HDAC8 inhibitor with IC50 of 90 nM, weakly inhibit HDAC1, HDAC2, HDAC6 with IC50 of 1.7 uM, 3.9 uM and >50 uM. |
| PC-27700 |
MC2625
HDAC inhibitor
|
MC2625 is a potent histone deacetylase (HDAC) inhibitor, shows selective HDAC3 and HDAC6 inhibition with IC50 of 80 nM and 11 nM respectively, also potently reactivate HIV from latency with EC50 of 350 nM. |
