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首页-小分子抑制剂&激动剂-Epigenetics-HDAC-HDAC1 inhibitor L17h
HDAC1 inhibitor L17h

Chemical Structure : HDAC1 inhibitor L17h

CAS No.:

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HDAC1 inhibitor L17h

货号: PC-28562Not For Human Use, Lab Use Only.

HDAC inhibitor L17h is a potent and highly selective HDAC1 inhibitor, transcriptionally upregulates acyl-CoA synthetase long-chain family member 4 (ACSL4) expression, potentiates ferroptosis with arachidonic acid in ESCC.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

HDAC inhibitor L17h is a potent and highly selective HDAC1 inhibitor, transcriptionally upregulates acyl-CoA synthetase long-chain family member 4 (ACSL4) expression, potentiates ferroptosis with arachidonic acid in ESCC.

物理化学性质&存储条件

分子量 462.35
分子式 C24H20BrN3O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(E)-3-(4-((2-(4-bromophenyl)-5-methyl-1H-benzo[d]imidazol-1-yl)methyl)phenyl)-N-hydroxyacrylamide

参考文献

1. Meng Liu, et al. J Med Chem. 2026 Oct 8;69(19):22611-22636.

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