| Cat. No. |
Product Name |
Information |
| PC-25110 |
Martinostat
HDAC inhibitor
|
Martinostat is a potent, selective inhibitor for class I and class-IIb HDACs with IC50 of 0.3/2.0/0.6 nM for HDAC1/2/3 and 4.1 nM for HDAC6 respectively, >100-fold selectivity over other HDAC isoforms. |
| PC-24921 |
RM-3-22
HDAC inhibitor
|
RM-3-22 is a TAZQ-based hydroxamic acid derivative and potent HDAC inhibitor with IC50 of 49.9 nM, 68.5 nM, and 12.9 nM for HDAC1, HDAC3, and HDAC6 isoforms respectively. |
| PC-24777 |
MI-192
HDAC2/HDAC3 inhibitor
|
MI-192 is a potent, selective HDAC2 and HDAC3 inhibitor with IC50 of 30 nM and 16 nM, respectively. |
| PC-24323 |
Trichostatin A
HDAC inhibitor
|
Trichostatin A (TSA) is a potent and specific, irreversible inhibitor of class I/II HDACs with IC50 of 1.8 nM for HDAC. |
| PC-23992 |
DS-103
HDAC inhibitor
|
DS-103 is a potent HDAC inhibitor with IC50 of 29/123/23/367 nM for HDAC1/2/3/6, weakly inhibits HDAC8 and no activity against class IIa member HDAC4. |
| PC-23420 |
4-phenylbutyric acid
HDAC inhibitor
|
4-phenylbutyric acid (4-PBA) is a specific endoplasmic reticulum (ER) stress inhibitor, inhibits HDAC activity and increases histone acetylation levels. |
| PC-22801 |
HDAC6 inhibitor 5a
HDAC6 inhibitor
|
HDAC6 inhibitor 5a (MPI-5a) is potent and selective HDAC6 inhibitor with IC50 of 36 nM, >50-fold selectivity over other HDACs |
| PC-22791 |
Givinostat
HDAC inhibitor
|
Givinostat (ITF-2357) is a potent, orally active, pan-HDAC inhibitor with IC50 of 198 and 157 nM for HDAC1 and HDAC3, respectively. |
| PC-21844 |
RBC1HI
HDAC1/2 inhibitor
|
RBC1HI (Regenacy Brain Class I HDAC Inhibitor) is a novel specific small molecule HDAC1/HDAC2 inhibitor, attenuates behavioral manifestations of oxycodone withdrawal, especially in mice with neuropathic pain. |
| PC-21537 |
HR488B
HDAC1 inhibitor
|
HR488B is a potent, selective HDAC1 inhibitor with IC50 of 1.24 uM, effectively inhibits the proliferation of CRC cells. |
| PC-21412 |
Quisinostat
HDAC inhibitor
|
Quisinostat (JNJ-26481585) is potent, second-generation histone deacetylase (HDAC) inhibitor with IC50 of 0.11 nM-0.64 nM for HDAC1, HDAC2, HDAC4, HDAC10 and HDAC11. |
| PC-21408 |
NT160
class IIa HDAC inhibitor
|
NT160 is a high affinity, selective class-IIa histone deacetylase (HDAC) inhibitor with IC50 of 80 nM (HDAC4), 600-fold selectivity over HDAC2 and 27-fold selectivity over HDAC8. |
