欢迎访问ProbeChem中文网站，英文网站请访问www.probechem.com
    英文 |     中文

产品咨询: sales@probechem.com
订购: order@probechem.com

首页-小分子抑制剂&激动剂-Epigenetics-HDAC-MI-192
MI-192

Chemical Structure : MI-192

CAS No.: 1415340-63-4

加入收藏

MI-192 (MI192 )

货号: PC-24777Not For Human Use, Lab Use Only.

MI-192 is a potent, selective HDAC2 and HDAC3 inhibitor with IC50 of 30 nM and 16 nM, respectively.

规格 价格 库存 数量
25 mg Get quote
50 mg Get quote
100 mg Get quote
获取报价单
* 请选择数量再加入购物车
 or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

MI-192 is a potent, selective HDAC2 and HDAC3 inhibitor with IC50 of 30 nM and 16 nM, respectively.
MI-192 inhibits HDAC activity in HeLa cell nuclear extracts with IC50 of 1.5 uM.
MI-192 (0.1-0.4 uM) showed the greatest growth inhibitory effect against the leukemic cell lines.
MI-192 induced differentiation and was cytotoxic through promotion of apoptosis against the acute myeloid leukaemic cell lines U937, HL60 and Kasumi-1.

物理化学性质&存储条件

分子量 383.45
分子式 C24H21N3O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-(2-Aminophenyl)-4-((4-methylene-1-oxo-3,4-dihydroisoquinolin-2(1H)-yl)methyl)benzamide

参考文献

1. Boissinot M, et al. Leuk Res. 2012 Oct;36(10):1304-10.

备案号：沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

联系我们 sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

询单

  • *产品名称:
  • *姓名:
  • *邮箱:
  • *公司名称:
  • *询单数量:
  • *国籍:
  • 询单信息: