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首页-小分子抑制剂&激动剂-Epigenetics-HDAC

Request The Product List ofHDAC HDAC

Cat. No. Product Name Information
PC-21537

HR488B

HDAC1 inhibitor

HR488B is a potent, selective HDAC1 inhibitor with IC50 of 1.24 uM, effectively inhibits the proliferation of CRC cells.
PC-21520

YSR734

HDAC inhibitor

YSR734 is a first-in-class covalent HDACs inhibitor with IC50 of 0.109 uM, 0.154 uM and 0.143 uM for HDAC1, HDAC2, and HDAC3, sparing other deacetylases (HDAC4-HDAC10, IC50>10 uM).
PC-21394

PB118

HDAC6 inhibitor.

PB118 is a potent, selective HDAC6 inhibitor with IC50 of 5.6 nM, shows >1000 times selectively towards HDAC1, reduces alzheimer's disease neuropathology.
PC-21309

KPZ560

HDAC1/2 inhibitor

KPZ560 is a potent, HDAC1/2-selective inhibitor with IC50 of 12/68 nM, respectively.
PC-21304

Mz325

Sirt2/HDAC6 inhibitor

Mz325 is a potent, selective, dual inhibitor of Sirt2/HDAC6 with IC50 of 320/43 nM, respectively.
PC-21042

KD5170

Class I /II HDAC inhibitor

KD5170 (KD-5170) is a potent mercaptoketone-based Class I and II-histone deacetylase (HDAC) inhibitor with IC50 of 45 nM in HeLa cell-based histone H3 hyperacetylation assay.
PC-20671

TNG260

CoreDAC inhibitor

TNG260 (TNG-260) is a potent, CoREST-selective deacetylase (CoreDAC) inhibitor, inhibits HDAC1 with 10-fold selectivity over HDAC3 in cells.
PC-72740

NN-390

HDAC6 inhibitor.

NN-390 (NN390) is a potent, selective HDAC6 inhibitor with IC50 of 9.8 nM, >200-550-fold selectivity over other HDAC isoforms.

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