AMC-3-030

Chemical Structure : AMC-3-030

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货号: PC-26251Not For Human Use, Lab Use Only.

AMC-3-030 is a potent, dual HDAC6/proteasome inhibitor with IC50 of 884 nM for HDAC6 and IC50 of 4.17 nM in cell-free 20S proteasomal chymotrypsin-like activity assay.

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生物&药学活性

AMC-3-030 is a potent, dual HDAC6/proteasome inhibitor with IC50 of 884 nM for HDAC6 and IC50 of 4.17 nM in cell-free 20S proteasomal chymotrypsin-like activity assay.
AMC-3-030 is essentially inactive against HDAC1 (IC50 > 30 uM).

物理化学性质&存储条件

分子量	604.51
分子式	C32H41BN4O7
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N1-(2-(((R)-3-methyl-1-((3aR,4R,6R,7aS)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butyl)amino)-2-oxoethyl)-N4-((phenylcarbamoyl)oxy)terephthalamide

参考文献

1. Chan AM, et al. ACS Med Chem Lett. 2025 Dec 22;17(1):125-132.

AMC-3-030

生物&药学活性

物理化学性质&存储条件

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AMC-3-030

生物&药学活性

物理化学性质&存储条件

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