| Cat. No. |
Product Name |
Information |
| PC-21373 |
UTBinh-14
Urea transporter UT-B inhibitor
|
UTBinh-14 (UT-B-IN-1) is a potent, highly selective inhibitor for urea transporter UT-B with IC50 of 11 nM, with over a thousand-fold selectivity over UT-A. |
| PC-26603 |
E822-1968
UT-A2 inhibitor
|
E822-1968 is a highly potent and selective inhibitor of urea transporter UT-A2 with IC50 of 0.44 uM. |
| PC-26602 |
HQA2
UT-A inhibitor
|
UTAinh-A2 (HQA2) is a noncompetitive inhibitor of UT-A with IC50 of 5 uM for UT-A1, with10-fold selectivity against UT-B, inhibits urea transport mediated by hUT-A2 with IC50 of 3.66 uM. |
| PC-26601 |
UTA1inh-A1
UT-A inhibitor
|
UTA1inh-A1 is a noncompetitive inhibitor of UT-A with IC50 of 3.3 uM for UT-A1, with 5-fold selectivity against UT-B. |
| PC-26600 |
PU-48
UT-A/UT-B inhibitor
|
PU-48 is a selective inhibitor of urea transporters UT-A and UT-B with IC50 of 0.32 uM (UT-A1), inhibits UT-B-facilitated urea transport with IC50 of 0.21 uM, 0.21 in human, 0.33 uM in rat, and 2.1 uM for human, rat, and mouse. |
| PC-26599 |
UTAinh-B3
UT-A inhibitor
|
UTAinh-B3 (ATB3) is a selective competitive inhibitor of urea transporter UT-A2 with IC50 of 6.38 uM, shows 6-fold stronger inhibition potency toward UT-B. |
| PC-26598 |
UTAinh-F11
UT-A inhibitor
|
UTAinh-F11 (UT-A inhibitor CF11) is a selective uncompetitive inhibitor of urea transporter UT-A with IC50 of 2.78 uM for hUT-A2, has 10 times selectivity for UT-A1 than UT-B. |
| PC-26597 |
Urea transport inhibitor 25a
Urea transporter inhibitor
|
Urea transport inhibitor 25a is a competitive, orally available inhibitor of urea transporters with IC50 of 0.14 μM and 0.48 μM against UT-B in rats and mice, respectively, inhibits both UT-A1 and UT-B. |
| PC-26596 |
M353-0039
UT-A2 inhibitor
|
M353-0039 is a highly potent and selective inhibitor of urea transporter UT-A2 with IC50 of 0.35 uM, shows no detective activity against UT-A3 or UT-B. |
