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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Urea Transporter-HQA2
HQA2

Chemical Structure : HQA2

CAS No.: 1029723-92-9

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HQA2 (UTAinh-A2, UTA1inh-A2 )

货号: PC-26602Not For Human Use, Lab Use Only.

UTAinh-A2 (HQA2) is a noncompetitive inhibitor of UT-A with IC50 of 5 uM for UT-A1, with10-fold selectivity against UT-B, inhibits urea transport mediated by hUT-A2 with IC50 of 3.66 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

UTAinh-A2 (HQA2) is a noncompetitive inhibitor of UT-A with IC50 of 5 uM for UT-A1, with10-fold selectivity against UT-B, inhibits urea transport mediated by hUT-A2 with IC50 of 3.66 uM.

物理化学性质&存储条件

分子量 308.34
分子式 C18H16N2O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

8-hydroxy-N-(3-methoxybenzyl)quinoline-2-carboxamide

参考文献

1. Shen-Ming Huang, et al. Nat Commun. 2024 Nov 26;15(1):10226.

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