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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Urea Transporter-UTAinh-F11
UTAinh-F11

Chemical Structure : UTAinh-F11

CAS No.: 946260-91-9

UTAinh-F11 (UT-A inhibitor CF11)

货号: PC-26598Not For Human Use, Lab Use Only.

UTAinh-F11 (UT-A inhibitor CF11) is a selective uncompetitive inhibitor of urea transporter UT-A with IC50 of 2.78 uM for hUT-A2, has 10 times selectivity for UT-A1 than UT-B.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

UTAinh-F11 (UT-A inhibitor CF11) is a selective uncompetitive inhibitor of urea transporter UT-A with IC50 of 2.78 uM for hUT-A2, has 10 times selectivity for UT-A1 than UT-B.

物理化学性质&存储条件

分子量 430.92
分子式 C17H19ClN2O5S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(4-chloro-3-(1,1-dioxidoisothiazolidin-2-yl)phenyl)-2-methoxy-5-methylbenzenesulfonamide

参考文献

1. Shen-Ming Huang, et al. Nat Commun. 2024 Nov 26;15(1):10226.

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