| Cat. No. |
Product Name |
Information |
| PC-42397 |
Emodepside
Anthelmintic
|
Emodepside (PF 1022-221) is a semisynthetic derivative of PF1022A, and novel cyclo-depsipeptide anthelmintic which is efficacious against a variety of gastrointestinal nematodes. |
| PC-45382 |
Rafoxanide
|
Rafoxanide is a salicylanilide anthelmintic agent that also shows to be an allosteric inhibitor of SPAK and OSR1. |
| PC-45368 |
Buparvaquone
Antiprotozoal
|
Buparvaquone is a hydroxynaphthoquinone antiprotozoal drug related to parvaquone and atovaquone. |
| PC-45379 |
Mebendazole
|
Mebendazole is a highly effective, broad-spectrum antihelmintic by selectively inhibiting the synthesis of microtubules in parasitic worms, and by destroying extant cytoplasmic microtubes in their intestinal cells.. |
| PC-45158 |
Doramectin
Antibiotic
|
Doramectin is a derivative of ivermectin that approved for the treatment of parasites, is an active compound against S.mansoni in an NMRI mouse infection model. |
| PC-42044 |
NSC5844
Antimalarial
|
NSC5844 (RE-640) is a bis-quinoline with diverse biological activities, inhibits the growth of P. falciparum strains that are sensitive (D-6) and resistant (W-2) to chloroquine with IC50 of 17 and 27 nM, respectively. |
| PC-26055 |
MMV1581361
PfATP4 inhibitor
|
MMV1581361 is a potent inhibitor of Plasmodium falciparum ATP4 (PfATP4), inhibits 3D7 P. falciparum Strain with IC50 of 0.03 uM, disrupts Na+ ion homeostasis in P. falciparum. |
| PC-25995 |
SB5-171
PfCLK3 inhibitor
|
SB5-171 is a potent, covalent PfCLK3 inhibitor with IC50 of 10 nM, shows potent antiparasitic activity (EC50=104 nM). |
| PC-25928 |
IID432
T. cruzi Topo II inhibitor
|
IID432 (IID-432) is a highly potent inhibitor of Trypanosoma cruzi topoisomerase II (T. cruzi Topo II), shows potent activity against T. cruzi with EC50 of 8 nM. |
| PC-25444 |
Schistosome p97 inhibitor 739
Parasite p97 inhibitor
|
Schistosome p97 inhibitor 739 is a potent, selective and covalent inhibitor of parasite p97 with IC50 of 150 nM and 320 nM for S. mansoni and H. sapiens p97 respectively. |
| PC-25438 |
Clocinizine
Antiparasite
|
Clocinizine is a chlorinated analogue of cinnarizine, shows potent antischistosomal activity against both male and female parasites with EC50 and EC90 of 4.6 uM and 5.9 uM respectively. |
| PC-25297 |
Fexinidazole
T. brucei inhibitor
|
Fexinidazole (HOE 239) is an orally active, potent nitroimidazole antitrypanosomal agent, shows trypanocidal activity against T. brucei subspecies and strains with IC50 of 0.7-3.3 uM, has the potential for human sleeping sickness (HAT) caused by infection with T. brucei. |
