| Cat. No. |
Product Name |
Information |
| PC-60489 |
MMV019313
|
MMV019313 (MMV 019313, MMV-019313) is a potent, specific malaria bifunctional farnesyl/geranylgeranyl diphosphate synthase (FPPS/GGPPS) inhibitor with IC50 of 330 nM. |
| PC-60458 |
DSM265
PfDHODH inhibitor
|
DSM265 is a potent, highly selective, long-duration and orally bioavailable malaria DHODH (PfDHODH) inhibitor with IC50 of 0.01 ug/mL. |
| PC-60316 |
SCYX-7158
Anti-parasite
|
SCYX-7158 (AN-5568, Acoziborole) is an orally-active, CNS permeable benzoxaborole antiprotozoal agent. |
| PC-60315 |
GNF6702
T. cruzi proteasome inhibitor
|
GNF6702 (GNF 6702) is a selective, non-competitive inhibitor of the kinetoplastid proteasome, inhibits the chymotrypsin-like activity of the T. cruzi proteasome with IC50 of 35 nM. |
| PC-45381 |
Closantel sodium
FICD inhibitor
|
Closantel sodium is a veterinary anthelmintic with known proton ionophore activities, also is a small molecule inhibitor of the AMP transferase FICD with IC50 of 7.27 uM. |
| PC-45380 |
Closantel
FICD inhibitor
|
Closantel (FICD inhibitor C22) is a veterinary anthelmintic with known proton ionophore activities, also is a small molecule inhibitor of the AMP transferase FICD with IC50 of 7.27 uM. |
| PC-45409 |
Pyrimethamine
NRF2 inhibitor
|
Pyrimethamine (Pirimetamin, RP 4753) is a synthetic derivative of ethyl-pyrimidine with potent antimalarial properties, interferes with the regeneration of tetrahydrofolic acid from dihydrofolate by competitively inhibiting DHFR, also is a potent NRF2 inhibitor. |
| PC-42397 |
Emodepside
Anthelmintic
|
Emodepside (PF 1022-221) is a semisynthetic derivative of PF1022A, and novel cyclo-depsipeptide anthelmintic which is efficacious against a variety of gastrointestinal nematodes. |
| PC-45382 |
Rafoxanide
Antiparasite, SPAK inhibitor
|
Rafoxanide is a salicylanilide anthelmintic agent that also shows to be an allosteric inhibitor of SPAK and OSR1. |
| PC-45368 |
Buparvaquone
Antiprotozoal, TaPin1 inhibitor
|
Buparvaquone is a hydroxynaphthoquinone antiprotozoal agent that inhibits cytochrome b (Cyt b), shows significant activity against a range of Apicomplexa parasites, most notably Theileria and Babesia species, also inhibits TaPin1 (T. annulata Peptidyl Prolyl Isomerase Pin1) and blocks parasite transformation. |
| PC-45379 |
Mebendazole
Tubulin polymerization inhibitor, Hedgehog inhibitor, OCTN1 inhibitor
|
Mebendazole is a highly effective, broad-spectrum antihelmintic by selectively inhibiting the synthesis of microtubules in parasitic worms, and by destroying extant cytoplasmic microtubes in their intestinal cells.. |
| PC-45158 |
Doramectin
Antibiotic
|
Doramectin is a derivative of ivermectin that approved for the treatment of parasites, is an active compound against S.mansoni in an NMRI mouse infection model. |
