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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Parasite-WIN 4-88
WIN 4-88

Chemical Structure : WIN 4-88

CAS No.:

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WIN 4-88 (WIN4-88)

货号: PC-26689Not For Human Use, Lab Use Only.

WIN 4-88 is a potent small molecule inhibitor of Cryptosporidium parvum Calcium-dependent protein kinase 1 (CpCDPK1) with IC50 of 56 nM, exhibits growth inhibition of zoonotic C. parvum, anthroponotic C. parvum and C. hominis Tu502 with EC50 of 42, 30 and 62 nM respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

WIN 4-88 is a potent small molecule inhibitor of Cryptosporidium parvum Calcium-dependent protein kinase 1 (CpCDPK1) with IC50 of 56 nM, exhibits growth inhibition of zoonotic C. parvum, anthroponotic C. parvum and C. hominis Tu502 with EC50 of 42, 30 and 62 nM respectively.

物理化学性质&存储条件

分子量 560.02
分子式 C25H26ClN5O6S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

4-((6-(2-chloro-4-methoxyphenyl)-8-(2,3-dihydroxypropyl)-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)-N,N-dimethylbenzenesulfonamide

参考文献

1. Wijitrmektong W, et al. J Infect Dis. 2026 May 4:jiag242.

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