PfHsp70-1 inhibitor AMK3

Chemical Structure : PfHsp70-1 inhibitor AMK3

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货号: PC-27251Not For Human Use, Lab Use Only.

PfHsp70-1 inhibitor AMK3 is a potent, high affinity and selective inhibitor of Plasmodium falciparum chaperone PfHsp70-1 with MST Kd of 0.82 uM, binds to the PfHsp70-1 N-terminal NBD and competes for ATP binding, has >25-fold for PfHsp70-1 over the human homolog HSPA1A.

规格	价格	库存	数量
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50 mg		Get quote
100 mg		Get quote

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生物&药学活性

物理化学性质&存储条件

分子量	395.43
分子式	C22H17N7O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(4-((6-(1H-imidazol-1-yl)pyrimidin-4-yl)amino)phenyl)-1H-indole-3-carboxamide

参考文献

1. Keeler AM, et al. Antimicrob Agents Chemother. 2026 Jul 2:e0046626.