| Cat. No. |
Product Name |
Information |
| PC-61006 |
GNF-Pf-5660
|
GNF-Pf-5660 is an antimalarial candidate that demonstrates potent blood-stage and transmission-blocking activity, shows potent ABS activity (IC50 <25 nM) against drug-sensitive 3D7 and multidrug-resistant Dd2 parasites. |
| PC-60489 |
MMV019313
|
MMV019313 (MMV 019313, MMV-019313) is a potent, specific malaria bifunctional farnesyl/geranylgeranyl diphosphate synthase (FPPS/GGPPS) inhibitor with IC50 of 330 nM. |
| PC-60458 |
DSM265
PfDHODH inhibitor
|
DSM265 is a potent, highly selective, long-duration and orally bioavailable malaria DHODH (PfDHODH) inhibitor with IC50 of 0.01 ug/mL. |
| PC-60316 |
SCYX-7158
Anti-parasite
|
SCYX-7158 (AN-5568, Acoziborole) is an orally-active, CNS permeable benzoxaborole antiprotozoal agent. |
| PC-60315 |
GNF-6702
|
GNF-6702 (GNF6702) is a selective, non-competitive inhibitor of the kinetoplastid proteasome, inhibits the chymotrypsin-like activity of the T. cruzi proteasome with IC50 of 35 nM. |
| PC-45380 |
Closantel
FICD inhibitor
|
Closantel (FICD inhibitor C22) is a veterinary anthelmintic with known proton ionophore activities, also is a small molecule inhibitor of the AMP transferase FICD with IC50 of 7.27 uM. |
| PC-45409 |
Pyrimethamine
NRF2 inhibitor
|
Pyrimethamine (Pirimetamin, RP 4753) is a synthetic derivative of ethyl-pyrimidine with potent antimalarial properties, interferes with the regeneration of tetrahydrofolic acid from dihydrofolate by competitively inhibiting DHFR, also is a potent NRF2 inhibitor. |
| PC-45382 |
Rafoxanide
|
Rafoxanide is a salicylanilide anthelmintic agent that also shows to be an allosteric inhibitor of SPAK and OSR1. |
| PC-45368 |
Buparvaquone
Antiprotozoal
|
Buparvaquone is a hydroxynaphthoquinone antiprotozoal drug related to parvaquone and atovaquone. |
| PC-45379 |
Mebendazole
|
Mebendazole is a highly effective, broad-spectrum antihelmintic by selectively inhibiting the synthesis of microtubules in parasitic worms, and by destroying extant cytoplasmic microtubes in their intestinal cells.. |
| PC-24762 |
Endochin
T. gondii bc1 inhibitor
|
Endochin is an antimalarial agent, inhibits T. gondii growth in vitro (IC50=0.003 nM), inhibits inhibited T.gondii cytochrome c reduction with IC50 of 8.2 nM. |
| PC-24761 |
ELQ-271
T. gondii bc1 inhibitor
|
ELQ-271 is a potent, orally bioavailable inhibitor of T. gondii growth in vitro (IC50=0.1 nM) and is effective against acute and latent toxoplasmosis in mice, inhibits cytochrome c reduction by the T. gondii cytochrome bc(1) complex. |
