| Cat. No. |
Product Name |
Information |
| PC-24569 |
Dabuzalgron
α1A-AR agonist
|
Dabuzalgron (Ro 115-1240) is an orally active and selective α-1A adrenergic receptor agonist with pKi of 7.39 for the displacement of [3H]-prazosin binding to CHO-K1 membranes. |
| PC-24568 |
CCF219B
α1A-AR PAM
|
CCF219B (Compound 3, Cmpd-3) is a potent, selective positive allosteric modulator of the α1A-adrenergic receptor (α1A-AR) with an affinity of 30 nM, 10-50-fold selectivity against the α1B- and α1D-AR subtypes. |
| PC-24491 |
Bisoprolol
β1AR antagonist
|
Bisoprolol is a second-generation, highly selective beta-1 adrenergic receptor (β1AR) antagonist with little activity on β2AR. |
| PC-23742 |
Carvedilol
β adrenergic receptor antagonist
|
Carvedilol (BM 14190) is a non-selective β adrenergic receptor (beta-AR) blocker, inhibits lipid peroxidation in a dose-dependent manner with IC50 of 5 uM, also is an autophagy inducer that inhibits the NLRP3 inflammasome. |
| PC-23382 |
Acepromazine maleate
α-adrenoceptor antagonist
|
Acepromazine (Acetopromazine) is a phenothiazine tranquilizeran and alpha-adrenoceptor antagonist, shows antipsychotic activity. |
| PC-23254 |
Efaroxan hydrochloride
α2AR antagonist, I1R antagonist
|
Efaroxan hydrochloride is a potent, selective and orally active α2-adrenoceptor (α2AR) antagonist, also is a selective I1 imidazoline receptor (I1R)antagonist. |
| PC-23250 |
Clonidine hydrochloride
α2AR agonist
|
Clonidine hydrochloride is a potent alpha 2-adrenergic receptor (α2AR) agonist with Ki of 3.8 nM, also binds to I1 imidazoline receptor (I1R) with Ki of 14.1 nM, a centrally acting antihypertensive agent. |
| PC-23249 |
Clonidine
α2AR agonist
|
Clonidine is a potent alpha 2-adrenergic receptor (α2AR) agonist with Ki of 3.8 nM, also binds to I1 imidazoline receptor (I1R) with Ki of 14.1 nM, a centrally acting antihypertensive agent. |
| PC-23223 |
Apraclonidine hydrochloride
α2 adrenoceptor agonist
|
Apraclonidine hydrochloride (Aplonidine, ALO 2145, ) is a potent and selective alpha2-adrenergic receptor agonist, has the ability to elevate the eye lid, also has been used as a diagnostic test in Horner's syndrome. |
| PC-22867 |
AGN-762
α2B/α2C adrenergic receptor activator
|
AGN-762 is a selective activator of α2B- and α2C-adrenergic receptor subtypes, but not the α2A subtype. |
| PC-22600 |
WB4101
α1A adrenoceptor antagonist
|
WB4101 is a potent, α1A-adrenergic selective antagonist with pKB value of 8.9 in rabbit aorta. |
| PC-22446 |
ATR-127
β2/β3-adrenoceptor agonist
|
ATR-127 is a highly effective β2- and β3-adrenoceptors (ARs) agonist with pEC50 of 6.53 and 5.5 for rat β2-AR and mouse β3-AR, respectively. |
