mTOR (inhibitors, antagonists, agonists)-ProbeChem.com

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Cat. No.	Product Name	Information
PC-45649	Seco Rapamycin sodium salt	Seco-rapamycin is the first in vivo open-ring metabolite of rapamycin that does not affect mTOR..
PC-45851	KU-0063794 mTOR inhibitor	KU-0063794 is a potent, specific, cell permeant inhibitor of mTOR with IC50 of 10 nM for both mTORC1 and mTORC2.
PC-42157	WYE-125132 mTOR inhibitor	A potent, specific, ATP-competitive and orally active mTOR inhibitor with IC50 of 0.19 nM.
PC-42608	PP242 mTOR inhibitor	Torkinib (PP242) is a potent, specific active-site inhibitor of mTOR with IC50 of 30 and 58 nM for mTORC1 and mTORC2, respectively.
PC-42576	AZD-8055 mTOR inhibitor	AZD-8055 is a potent, selective, ATP-competitive and orally bioavailable mTOR inhibitor with IC50 of 0.8 nM.
PC-45098	Onatasertib mTOR inhibitor	Onatasertib (CC-223, ATG-008) is a potent, selective, and orally bioavailable inhibitor of mTOR kinase with IC50 of 16 nM.
PC-45902	Deforolimus mTOR inhibitor	Deforolimus (AP-23573, MK-8669, Ridaforolimus) potent, selective mTOR inhibitor with IC50 of 0.2 nM in HT-1080 cell line.
PC-42463	Everolimus mTOR inhibitor	Everolimus (RAD001) is a potent, highly specific, orally active mTOR inhibitor with IC50 of 5-6 nM for binding to FKBP-12 or FKBP-12 complexed to mTOR.
PC-42092	CZ-415 mTOR inhibitor	CZ-415 (CZ415) potent, highly selective, ATP-competitive and orally bioavailable mTOR inhibitor with pKd of 8.2.
PC-45461	mTOR-IN-1 mTOR inhibitor	mTOR-IN-1 is a potent and selective mTOR inhibitor with Ki of 1.5 nM.
PC-42577	OSI-027 mTOR inhibitor	OSI-027 (ASP7486) is a potent and selective inhibitor of mTORC1 and mTORC2 with IC50 of 22 nM and 65 nM, respectively.
PC-42038	PQR-620 mTOR inhibitor	PQR-620 (PQR620) is a potent and selective, brain penetrant inhibitor of mTORC1/2, displays >1000-fold selectivity towards mTOR over PI3Kα in enzymatic binding assays.

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